TvY486_0901060

cyclophilin type peptidyl-prolyl cis-trans isomerase, putative
Trypanosoma vivax Y486 OG6: OG6_109053 OG7: OG7_0000556 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0403040 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_1005070
Elongation factor G1, mitochondrial, putative
— OG6
TvY486_1004990 ⚠
protein phosphatase 2C-like, putative
— OG6
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TvY486_1115000
Alpha/beta hydrolase family, putative
— OG6
TvY486_0805170
dihydroorotase, putative
— OG6
TvY486_1004460 ⚠
stress-inducible protein STI1-like, putative
— OG6
TvY486_0025450
mevalonate diphosphate decarboxylase
— OG6
TvY486_0900800
deoxyhypusine hydroxylase, putative
— OG6
TvY486_0301960
hypothetical protein, conserved (fragment)
— OG6
TvY486_0904530 ⚠
Co-chaperone protein P23
— OG6
TvY486_0100550
Mitochondrial Editosome-like Complex TUTase
— OG6
TvY486_0502590
hypothetical protein, conserved
— OG6
TvY486_0600780
PITH domain-containing protein
— OG6
TvY486_1115680 ⚠
protein phosphatase 2C, putative
— OG6
TvY486_0503540
hypothetical protein, conserved
— OG6
TvY486_0302960
U-box domain containing protein, putative
— OG6
TvY486_0007940 ⚠
tviv623d01.q1k_22, TPR-repeat protein, putati
— OG6
TvY486_1116420
hypothetical protein, conserved
— OG6
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— OG6
TvY486_0303220
carnitine/choline acetyltransferase, putative
— OG6
TvY486_0703730
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
TvY486_0027890
hypothetical protein, conserved
— OG6
TvY486_1013280
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
TvY486_1115520
phosphomannose isomerase, putative
— OG6
TvY486_0200810
transcription elongation factor s-II, putativ
— OG6
TvY486_0403510 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG6
TvY486_0038700 ⚠
ubiquitin hydrolase, putative
— OG6
TvY486_1101230
UBA/TS-N domain containing protein, putative
— OG6
TvY486_0304700
UBX domain-containing protein
— OG6
TvY486_0201650 ⚠
protein phosphatase 2C, putative
— OG6
TvY486_0803180
Mitogen-activated protein kinase 10, putative
— OG6
TvY486_1116090
hypothetical protein, conserved
— OG6
TvY486_1011250
nicotinate phosphoribosyltransferase, putativ
— OG6
TvY486_1117420
enoyl-CoA hydratase/isomerase family protein,
— OG6
TvY486_0301440
hypothetical protein, conserved
— OG6
TvY486_1116890 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG6
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG6
TvY486_1013590
pyruvate kinase 1, putative, (fragment)
— OG6
TvY486_1013710
N-myristoyl transferase, putative
— OG6
TvY486_1005340
eukaryotic translation initiation factor 6 (e
— OG6
TvY486_0402570
pyroglutamyl-peptidase I, putative
— OG6
TvY486_1110870
Biotin--acetyl-CoA-carboxylase ligase, putati
— OG6
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TvY486_1007790
2,3-bisphosphoglycerate-independent phosphogl
— OG6
TvY486_0300560
TAP42-like family, putative
— OG6
TvY486_0800330
serine/threonine kinase, putative
— OG6
TvY486_0807690 ⚠
amino acid transporter
— OG6
TvY486_0805130
transaldolase, putative
— OG6
TvY486_0701820
GMP synthase [glutamine-hydrolysing], (fragme
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.