TvY486_0400120

Phosphatidylinositol 3-kinase tor2
Trypanosoma vivax Y486 OG6: OG6_100794 OG7: OG7_0001934 315 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 315 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0806870 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TvY486_0806860 ⚠
acetoin dehydrogenase e3 component, putative,
— OG7
TvY486_0002690 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TvY486_1011810 ⚠
hypothetical protein, conserved
— Both
TvY486_1111590 ⚠
glycosyl hydrolase, putative
— OG7
TvY486_1116880 ⚠
CS domain/TPR repeat, putative
— OG7
TvY486_1001080 ⚠
dynein arm light chain, putative
— OG7
TvY486_1105690 ⚠
dynein arm light chain, putative
— OG7
TvY486_1014210 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
TvY486_0903390 ⚠
adenylate kinase, putative
— OG7
TvY486_0201936 ⚠
adenylate kinase, putative, (fragment)
— OG7
TvY486_1004350 ⚠
adenylate kinase, putative
— OG7
TvY486_0503420 ⚠
adenylate kinase, putative
— OG7
TvY486_1000790 ⚠
adenylate kinase, putative
— OG7
TvY486_1012850 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
TvY486_0903320 ⚠
hypothetical protein, conserved
— OG7
TvY486_0501990 ⚠
hypothetical protein, conserved
— OG7
TvY486_0503160 ⚠
hypothetical protein, conserved
— OG7
TvY486_1108210 ⚠
Cell division control protein 48, putative
— OG7
TvY486_0805690 ⚠
hypothetical protein, conserved
— OG7
TvY486_0705355 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0701210 ⚠
DNA polymerase sigma-like protein, putative
— OG7
TvY486_0800550 ⚠
DNA polymerase sigma, putative
— OG7
TvY486_0902970 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1104500 ⚠
ATP-dependent RNA helicase, putative
— OG7
TvY486_1115360 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TvY486_0501670 ⚠
ATP-dependent RNA helicase, putative
— OG7
TvY486_0802790 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TvY486_1107670 ⚠
neurobeachin/beige protein, putative
— OG7
TvY486_1002800 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TvY486_1006120 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_0200840 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0804650 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TvY486_0806890 ⚠
RNA polymerase IIA largest subunit, (fragment
— OG7
TvY486_0300660 ⚠
PRP38 family, putative
— OG7
TvY486_1107690 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_0404370 ⚠
RNA polymerase IIA largest subunit, (fragment
— OG7
TvY486_0013050 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0502670 ⚠
hypothetical protein, conserved
— OG7
TvY486_0706450 ⚠
Kinetochore interacting protein 5, putative
— OG7
TvY486_1013490 ⚠
tubulin-specific chaperone, putative
— OG7
TvY486_0601360 ⚠
hypothetical protein, conserved
— OG7
TvY486_1117890 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
TvY486_0603060 ⚠
tubulin-tyrosine ligase-like protein, conserv
— OG7
TvY486_0200310 ⚠
hypothetical protein, conserved
— OG7
TvY486_0402370 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1000410 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TvY486_0100690 ⚠
tubulin-tyrosine ligase, putative
— OG7
TvY486_0404040 ⚠
hypothetical protein, conserved
— OG7
TvY486_0904090 ⚠
tubulin tyrosine ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.