TvY486_1115360

ATP-dependent DNA DEAD/DEAH box helicase, putative (fragment)
Trypanosoma vivax Y486 OG6: OG6_104328 OG7: OG7_0001850 130 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 130 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0905100 ⚠
protein kinase A catalytic subunit, (fragment
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— Both
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_0806620 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TvY486_1007300 ⚠
cullin, putative
— OG7
TvY486_1112430 ⚠
cullin 2, putative
— OG7
TvY486_0300680 ⚠
cullin 4B, putative
— OG7
TvY486_0805490 ⚠
cullin, putative
— OG7
TvY486_1006870 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TvY486_1101350 ⚠
Right handed beta helix region/Periplasmic co
— OG7
TvY486_1014910 ⚠
ABC transporter, putative
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1114830 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0700445 ⚠
zinc finger protein, putative
— OG7
TvY486_0906610 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0706700 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TvY486_0704260 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TvY486_0100900 ⚠
phosphatidylinositol 3-kinase, putative, (fra
— OG7
TvY486_1002800 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TvY486_0200840 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0803030 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
TvY486_0029580 ⚠
hypothetical protein
— OG7
TvY486_0100010 ⚠
DNA-directed RNA polymerase III, putative (fr
— OG7
TvY486_1014740 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TvY486_0304910 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
TvY486_0705180 ⚠
SpoU rRNA Methylase family, putative
— OG7
TvY486_0402270 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TvY486_0700650 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1100210 ⚠
RNA-binding protein, putative (fragment)
— OG7
TvY486_0024850 ⚠
hypothetical protein, conserved in T. vivax
— OG7
TvY486_1006120 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_0902520 ⚠
hypothetical protein, conserved
— OG7
TvY486_1115410 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TvY486_0905570 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TvY486_1107670 ⚠
neurobeachin/beige protein, putative
— OG7
TvY486_0301540 ⚠
translation elongation factor EF-2, putative
— OG7
TvY486_0906670 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_1003480 ⚠
RNA-binding protein, putative, (fragment)
— OG7
TvY486_0902710 ⚠
exosome complex exonuclease RRP40, putative
— OG7
TvY486_0045710 ⚠
proteasome regulatory non-ATP-ase subunit, pu
— OG7
TvY486_1001550 ⚠
proteasome regulatory non-ATP-ase subunit 5,
— OG7
TvY486_0200420 ⚠
hypothetical protein, conserved
— OG7
TvY486_1014000 ⚠
19S proteasome non-atpase subunit 8
— OG7
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_1003160 ⚠
ABC transporter protein, putative
— OG7
TvY486_0043450 ⚠
ABC transporter, putative (fragment)
— OG7
TvY486_0043440 ⚠
hypothetical protein (fragment)
— OG7
TvY486_1116920 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.