TvY486_0806620

acetyl-CoA carboxylase (fragment)
Trypanosoma vivax Y486 OG6: OG6_101052 OG7: OG7_0001434 193 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 193 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0502330 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
TvY486_1009350 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TvY486_1103090 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TvY486_0502575 ⚠
ribose-phosphate pyrophosphokinase, putative,
— +5 more Both
TvY486_1115360 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TvY486_0802790 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TvY486_1104500 ⚠
ATP-dependent RNA helicase, putative
— Both
TvY486_1002800 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
TvY486_0806890 ⚠
RNA polymerase IIA largest subunit, (fragment
— Both
TvY486_0404370 ⚠
RNA polymerase IIA largest subunit, (fragment
— Both
TvY486_0804650 ⚠
DNA-directed rna polymerase I largest subunit
— Both
TvY486_0501670 ⚠
ATP-dependent RNA helicase, putative
— Both
TvY486_0804880 ⚠
WW domain containing protein, putative
— OG7
TvY486_1007260 ⚠
ATP-dependent DEAD/H RNA helicae, putative
— OG7
TvY486_0704500 ⚠
proteasome alpha 3 subunit, putative
— OG7
TvY486_0300190 ⚠
proteasome alpha 7 subunit, (fragment)
— OG7
TvY486_1006870 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TvY486_0805490 ⚠
cullin, putative
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— OG7
TvY486_1007300 ⚠
cullin, putative
— OG7
TvY486_1112430 ⚠
cullin 2, putative
— OG7
TvY486_1008070 ⚠
T-complex protein 1, theta subunit, putative
— OG7
TvY486_1103330 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TvY486_0803610
hypothetical protein, conserved (fragment)
— OG7
TvY486_0905200 ⚠
T-complex protein 1, eta subunit, putative, t
— OG7
TvY486_1101820 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1008260 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_1101350
Right handed beta helix region/Periplasmic co
— Both
TvY486_0703780
'Cold-shock' DNA-binding domain containing pr
— Both
TvY486_0043840
hypothetical protein (fragment)
— Both
TvY486_0906800
helicase, putative, (fragment)
— OG6
TvY486_1003190
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TvY486_0802330
hypothetical protein, conserved
— Both
TvY486_0300680 ⚠
cullin 4B, putative
— Both
TvY486_0604310
ATP synthase, epsilon chain, putative
— Both
TvY486_0403630
hypothetical protein, conserved
— Both
TvY486_0200460
proteasome regulatory non-ATPase subunit 6
— Both
TvY486_1107780
proteasome beta 3 subunit, putative
— Both
TvY486_0803030
AKAP7 2'5' RNA ligase-like domain containing
— Both
TvY486_0403520 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0302200 ⚠
hypothetical protein, conserved
— OG7
TvY486_0602010 ⚠
hypothetical protein, conserved
— OG7
TvY486_0902520
hypothetical protein, conserved
— OG7
TvY486_0100010 ⚠
DNA-directed RNA polymerase III, putative (fr
— OG7
TvY486_0807380 ⚠
hypothetical protein, conserved
— Both
TvY486_0704260
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— Both
Page 1 of 4
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.