TvY486_1103330

T-complex protein 1, zeta subunit, putative

Trypanosoma vivax Y486 OG6: OG6_101716 OG7: OG7_0001068 106 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 106 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_0802590 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG6 Tb927.11.14250 ↔ Tb927.11.3240 OG6 TCSYLVIO_000177 ↔ TCSYLVIO_003488 OG6 TCSYLVIO_003488 ↔ TCSYLVIO_004200 OG6 LdBPK_131400.1 ↔ LdBPK_231460.1 +86 more	Both
TvY486_0029620 ⚠ chaperonin containing t-complex protein, puta	—	OG6 Tb927.11.14250 ↔ Tb927.11.3240 OG6 TCSYLVIO_000177 ↔ TCSYLVIO_003488 OG6 TCSYLVIO_003488 ↔ TCSYLVIO_004200 OG6 LdBPK_131400.1 ↔ LdBPK_231460.1 +86 more	Both
TvY486_1001000 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 Tb927.10.1060 ↔ Tb927.11.3240 OG6 TCSYLVIO_003488 ↔ TCSYLVIO_008271 OG6 LdBPK_131400.1 ↔ LdBPK_211330.1 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005312 +83 more	Both
TvY486_1101820 ⚠ T-complex protein 1, beta subunit, putative	—	OG6 Tb927.11.1900 ↔ Tb927.11.3240 OG6 TCSYLVIO_003488 ↔ TCSYLVIO_005500 OG6 LdBPK_131400.1 ↔ LdBPK_271150.1 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005312 +83 more	Both
TvY486_1117770 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_003488 ↔ TCSYLVIO_005312 OG6 Tb927.11.16760 ↔ Tb927.11.3240 OG6 LdBPK_131400.1 ↔ LdBPK_323470.1 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005312 +83 more	Both
TvY486_0905200 ⚠ T-complex protein 1, eta subunit, putative, t	—	OG6 TCSYLVIO_003488 ↔ TCSYLVIO_005772 OG6 LdBPK_131400.1 ↔ LdBPK_353900.1 OG6 Tb927.11.3240 ↔ Tb927.9.11270 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005312 +83 more	Both
TvY486_1008070 ⚠ T-complex protein 1, theta subunit, putative	—	OG6 TCSYLVIO_003488 ↔ TCSYLVIO_004584 OG6 Tb927.10.8190 ↔ Tb927.11.3240 OG6 LdBPK_131400.1 ↔ LdBPK_367240.1 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005312 +83 more	Both
TvY486_1000170 ⚠ proteasome subunit alpha type-5, putative	—	OG6 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 +41 more	Both
TvY486_0201510 ⚠ Phosducin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_003488 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_000453 OG7 Tb927.11.1900 ↔ Tb927.2.4850 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005312 +6 more	Both
TvY486_1117000 ⚠ ATP binding protein-like protein, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_003488 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_000453 OG7 Tb927.11.1900 ↔ Tb927.2.4850 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005312 +6 more	Both
TvY486_0300190 ⚠ proteasome alpha 7 subunit, (fragment)	—	OG6 TCSYLVIO_003488 ↔ TCSYLVIO_003527 OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 +41 more	Both
TvY486_1000230 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_003488 ↔ TCSYLVIO_009369 OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 +41 more	Both
TvY486_0904170 ⚠ 20S proteasome subunit, proteasome alpha 1 su	—	OG6 TCSYLVIO_003488 ↔ TCSYLVIO_005678 OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 +41 more	Both
TvY486_1107320 ⚠ proteasome alpha 7 subunit, putative, (fragme	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_003488 OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 +41 more	Both
TvY486_1005980 ⚠ proteasome subunit alpha type-1, putative	—	OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 OG7 Tb927.7.4420 ↔ Tb927.8.3150 +40 more	OG7
TvY486_0704500 ⚠ proteasome alpha 3 subunit, putative	—	OG7 Tb927.10.6030 ↔ Tb927.11.1900 OG7 Tb927.10.230 ↔ Tb927.11.3240 OG7 Tb927.10.6030 ↔ Tb927.11.16760 OG7 Tb927.7.4420 ↔ Tb927.8.3150 +40 more	OG7
TvY486_0502575 ⚠ ribose-phosphate pyrophosphokinase, putative,	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004731 +2 more	OG7
TvY486_0502330 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004731 +2 more	OG7
TvY486_1008420 ⚠ Galactose oxidase, central domain containing	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001589 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_004200 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005500 +4 more	OG7
TvY486_1003140 ⚠ acetyltransferase, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004519 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_008271	OG7
TvY486_1107270 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001704 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_008271	OG7
TvY486_1007650 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004617 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_004617 OG7 TCSYLVIO_004200 ↔ TCSYLVIO_004617 OG7 TCSYLVIO_004617 ↔ TCSYLVIO_005312 +3 more	OG7
TvY486_1002790 ⚠ eukaryotic translation initiation factor 5, p	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TvY486_0033450 ⚠ hypothetical protein, conserved in T. vivax (	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_011061 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_011061 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_011061 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_011061 +11 more	OG7
TvY486_1008260 ⚠ ubiquitin-protein ligase, putative, (fragment	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_009791 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_009791 +4 more	OG7
TvY486_1007150 ⚠ terminal uridylyltransferase 3, putative, (fr	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010483 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_010483 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_010483 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010483 +4 more	OG7
TvY486_0301890 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_008271	OG7
TvY486_0100220 ⚠ kelch domain-containing protein	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001589 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_004200 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005500 +4 more	OG7
TvY486_0401320 ⚠ ribosomal RNA processing protein 6, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_003804 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_008271	OG7
TvY486_1005840 ⚠ Galactose oxidase, central domain containing	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001589 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_004200 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005500 +4 more	OG7
TvY486_0701340 ⚠ RET2, RNA editing complex MP57, putative, RNA	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010483 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_010483 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_010483 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010483 +4 more	OG7
TvY486_1107780 ⚠ proteasome beta 3 subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001736 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_008271	OG7
TvY486_0503360 ⚠ Galactose oxidase, central domain/Domain of u	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001589 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_004200 OG7 TCSYLVIO_001589 ↔ TCSYLVIO_005500 +4 more	OG7
TvY486_0400150 ⚠ coatomer alpha subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_003688 OG7 TCSYLVIO_003688 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_003688 ↔ TCSYLVIO_004200 OG7 TCSYLVIO_003688 ↔ TCSYLVIO_005500 +3 more	OG7
TvY486_0806620 ⚠ acetyl-CoA carboxylase (fragment)	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_008271	OG7
TvY486_1004580 ⚠ elongation factor 2, putative, (fragment)	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004074 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_004074 OG7 TCSYLVIO_004074 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004074 ↔ TCSYLVIO_004200 +4 more	OG7
TvY486_1007260 ⚠ ATP-dependent DEAD/H RNA helicae, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_008271	OG7
TvY486_0020590 ⚠ hypothetical protein, conserved in T.vivax	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_011061 OG7 TCSYLVIO_004584 ↔ TCSYLVIO_011061 OG7 TCSYLVIO_003488 ↔ TCSYLVIO_011061 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_011061 +11 more	OG7
TvY486_0101120 ⚠ alpha tubulin, putative	—	OG7 Tb927.1.2330 ↔ Tb927.11.3240	OG7
TvY486_1110220 ⚠ eukaryotic translation initiation factor 3 su	—	OG7 Tb927.10.1060 ↔ Tb927.11.9610 OG7 Tb927.11.9610 ↔ Tb927.9.11270 OG7 Tb927.11.9610 ↔ Tb927.8.3150	OG7
TvY486_1101810 ⚠ Serine-threonine kinase receptor-associated p	—	OG7 Tb927.10.1060 ↔ Tb927.11.9610 OG7 Tb927.11.9610 ↔ Tb927.9.11270 OG7 Tb927.11.9610 ↔ Tb927.8.3150	OG7
TvY486_0000730 ⚠ eukaryotic translation initiation factor, put	—	OG7 Tb927.10.1060 ↔ Tb927.11.9610 OG7 Tb927.11.9610 ↔ Tb927.9.11270 OG7 Tb927.11.9610 ↔ Tb927.8.3150	OG7
TvY486_1116860 ⚠ proteasome regulatory non-ATP-ase subunit 7,	—	OG7 Tb927.10.1060 ↔ Tb927.11.16030	OG7
TvY486_1110250 ⚠ eukaryotic translation initiation factor, put	—	OG7 Tb927.10.1060 ↔ Tb927.11.9610 OG7 Tb927.11.9610 ↔ Tb927.9.11270 OG7 Tb927.11.9610 ↔ Tb927.8.3150	OG7
TvY486_0300320 ⚠ tubulin gamma chain (fragment)	—	OG7 Tb927.1.2330 ↔ Tb927.11.3240	OG7
TvY486_0101150 ⚠ alpha tubulin, putative, (fragment)	—	OG7 Tb927.1.2330 ↔ Tb927.11.3240	OG7
TvY486_1111860 ⚠ tubulin delta chain	—	OG7 Tb927.1.2330 ↔ Tb927.11.3240	OG7
TvY486_0400130 ⚠ proteasome beta 7 subunit	—	OG7 Tb927.4.430 ↔ Tb927.8.3150 OG7 Tb927.11.14250 ↔ Tb927.4.430	OG7
TvY486_0101130 ⚠ alpha tubulin, putative	—	OG7 Tb927.1.2330 ↔ Tb927.11.3240	OG7
TvY486_1001090 ⚠ epsilon tubulin, putative, (fragment)	—	OG7 Tb927.1.2330 ↔ Tb927.11.3240	OG7

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