TvY486_0301890

ATP-dependent DEAD/H RNA helicase, putative
Trypanosoma vivax Y486 OG6: OG6_105684 OG7: OG7_0002665 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1015470 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TvY486_1116170 ⚠
Importin subunit beta-4, putative
— OG7
TvY486_1117250 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— OG7
TvY486_0802170 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TvY486_0301540 ⚠
translation elongation factor EF-2, putative
— OG7
TvY486_0906080 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TvY486_1004580 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_0500090 ⚠
methyltransferase, putative
— OG7
TvY486_1101820 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TvY486_0905200 ⚠
T-complex protein 1, eta subunit, putative, t
— OG7
TvY486_1103330 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TvY486_1008070 ⚠
T-complex protein 1, theta subunit, putative
— OG7
TvY486_0704500 ⚠
proteasome alpha 3 subunit, putative
— OG7
TvY486_1000170 ⚠
proteasome subunit alpha type-5, putative
— OG7
TvY486_1006040 ⚠
proteasome subunit beta type-5, putative
— OG7
TvY486_0502575 ⚠
ribose-phosphate pyrophosphokinase, putative,
— OG7
TvY486_1005980 ⚠
proteasome subunit alpha type-1, putative
— OG7
TvY486_0906770 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0300390 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TvY486_0600970 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TvY486_0400240 ⚠
hypothetical protein, conserved
— OG7
TvY486_1010440 ⚠
hypothetical protein, conserved
— OG7
TvY486_0602010 ⚠
hypothetical protein, conserved
— OG7
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0501330 ⚠
ecotin, putative
— OG7
TvY486_1007860 ⚠
replication factor C subunit 3, putative
— OG7
TvY486_0023700 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1111150 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_0305050 ⚠
nuclear transcription factor, putative
— OG7
TvY486_0905580 ⚠
predicted zinc finger protein, zinc finger pr
— OG7
TvY486_0010920 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0029580 ⚠
hypothetical protein
— OG7
TvY486_0700445 ⚠
zinc finger protein, putative
— OG7
TvY486_0400410 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TvY486_1008760 ⚠
hypothetical protein, conserved
— OG7
TvY486_0403660 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TvY486_0100870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TvY486_1112790 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TvY486_1010490 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_0401560 ⚠
Carboxypeptidase-like protein
— OG7
TvY486_0800270 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0906750 ⚠
Importin 1
— OG7
TvY486_0705600 ⚠
TLD, putative
— OG7
TvY486_1006910 ⚠
hypothetical protein, conserved
— OG7
TvY486_1007580 ⚠
protein transport protein Sec23A, putative
— OG7
TvY486_0024850 ⚠
hypothetical protein, conserved in T. vivax
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.