TvY486_1116170

Importin subunit beta-4, putative
Trypanosoma vivax Y486 OG6: OG6_101397 OG7: OG7_0003452 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1102510 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_0603230 ⚠
heat shock 70 kDa protein, mitochondrial prec
— OG7
TvY486_0603280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— OG7
TvY486_0200840 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1013040 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TvY486_1003670 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TvY486_0503360 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
TvY486_0601730 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1009060 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
TvY486_0701770 ⚠
R3H domain containing protein, putative
— OG7
TvY486_1005840 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_1100300 ⚠
conserved protein
— OG7
TvY486_0301890 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TvY486_0500500 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TvY486_0403040 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0100220 ⚠
kelch domain-containing protein
— OG7
TvY486_0702940 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_0901110 ⚠
u6 snrna-associated sm-like protein, Sm- like
— OG7
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_0501740 ⚠
hypothetical protein, conserved
— OG7
TvY486_0602190 ⚠
small nuclear ribonucleoprotein Sm-E
— OG7
TvY486_1107670 ⚠
neurobeachin/beige protein, putative
— OG7
TvY486_0901320 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— OG7
TvY486_0300390 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TvY486_1010370 ⚠
hypothetical protein, conserved
— OG7
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_1004580 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TvY486_0043220 ⚠
hypothetical protein, conserved
— OG7
TvY486_0603220 ⚠
heat shock 70 kDa protein, mitochondrial prec
— OG7
TvY486_0502090 ⚠
zinc-finger protein ZPR1, putative
— OG7
TvY486_1107690 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_1104190 ⚠
hypothetical protein, conserved
— OG7
TvY486_1112460 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_1006120 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_1103570 ⚠
hypothetical protein, conserved
— OG7
TvY486_0501010 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TvY486_0401560 ⚠
Carboxypeptidase-like protein
— OG7
TvY486_1010490 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_0904540 ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
TvY486_0303268 ⚠
RNA binding protein, putative
— OG7
TvY486_0400240 ⚠
hypothetical protein, conserved
— Both
TvY486_1109880 ⚠
hypothetical protein, conserved
— OG7
TvY486_0703300 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TvY486_0901040 ⚠
endo-beta-N-acetylglucosaminidase, putative,
— OG7
TvY486_1115100 ⚠
small nuclear ribonucleoprotein Sm-G
— OG7
TvY486_0300500 ⚠
GTP-binding nuclear protein rtb2, putative
— Both
TvY486_0303520 ⚠
hypothetical protein, conserved
— Both
TvY486_0300970 ⚠
hypothetical protein, conserved
— Both
TvY486_0600970 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.