TvY486_1102510

metallo-peptidase, Clan MF, Family M17
Trypanosoma vivax Y486 OG6: OG6_105603 OG7: OG7_0003405 269 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 269 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0101320 ⚠
amidohydrolase, putative
— +7 more Both
TvY486_0101330 ⚠
amidohydrolase, putative
— +7 more Both
TvY486_0601730 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0601460 ⚠
hypothetical protein, conserved
— OG7
TvY486_1003670 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TvY486_1111170 ⚠
hypothetical protein, conserved
— +2 more Both
TvY486_1109070 ⚠
ribonuclease II-like protein, putative, (frag
— +1 more Both
TvY486_0500500 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TvY486_1009060 ⚠
isoleucyl-tRNA synthetase, putative
— Both
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— Both
TvY486_1108060 ⚠
rrp44p homologue, putative
— +1 more Both
TvY486_0902820 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TvY486_0901510 ⚠
DNA-damage inducible protein DDI1-like protei
— +1 more Both
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TvY486_0501740 ⚠
hypothetical protein, conserved
— OG7
TvY486_1001290 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TvY486_0034500 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0700230 ⚠
FYVE zinc finger, putative
— OG7
TvY486_0701710 ⚠
hypothetical protein, conserved
— OG7
TvY486_0041460 ⚠
chromatin binding protein, putative
— OG7
TvY486_1107690 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_1100700 ⚠
protein kinase, putative
— OG7
TvY486_0501270 ⚠
RNA pseudouridylate synthase, putative
— OG7
TvY486_1014970 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TvY486_0905580 ⚠
predicted zinc finger protein, zinc finger pr
— OG7
TvY486_0305050 ⚠
nuclear transcription factor, putative
— OG7
TvY486_1004640 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TvY486_1107120 ⚠
regulator of chromatin condensation, putative
— OG7
TvY486_0021110 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TvY486_0200880 ⚠
translation initiation factor IF-2, putative
— OG7
TvY486_1014960 ⚠
macrophage infectivity potentiator, precursor
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0801730 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TvY486_1102360 ⚠
mRNA export factor MEX67
— OG7
TvY486_0006090 ⚠
peptidylprolyl isomerase-like, putative (frag
— OG7
TvY486_1111190 ⚠
regulator of chromosome condensation 1-like p
— OG7
TvY486_0013050 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_1109550 ⚠
p21-C-terminal region-binding protein, putati
— OG7
TvY486_0303270 ⚠
heat shock protein, putative
— OG7
TvY486_1003780 ⚠
vacuolar ATP synthase subunit D, putative, (f
— OG7
TvY486_0904770 ⚠
synaptojanin (N-terminal domain), putative, (
— OG7
TvY486_0023660 ⚠
lipophosphoglycan biosynthetic protein, putat
— OG7
TvY486_0402120 ⚠
hypothetical protein, conserved
— OG7
TvY486_1013850 ⚠
Histone chaperone Rttp106-like, putative
— OG7
TvY486_1113650 ⚠
ubiquitin ligase, putative (fragment)
— OG7
TvY486_1105670 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TvY486_0503710 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.