TvY486_0601460

hypothetical protein, conserved
Trypanosoma vivax Y486 OG6: OG6_158251 OG7: OG7_0052285 195 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 195 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0503220
ubiquitin-activating enzyme E1, putative, (fr
— Both
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TvY486_1102350
phenylalanyl-tRNA synthetase, putative, (frag
— Both
TvY486_0600460
cysteinyl-tRNA synthetase, putative, (fragmen
— Both
TvY486_0805800 ⚠
tubulin folding cofactor D, putative, (fragme
— Both
TvY486_0032470 ⚠
hypothetical protein, conserved in T. vivax
— OG6
TvY486_0502690
WD domain, G-beta repeat, putative
— Both
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_1103120
ribosome assembly protein RRB1, putative
— Both
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— Both
TvY486_1102510 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_0020590 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0804120 ⚠
hypothetical protein, conserved
— Both
TvY486_0027600 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
TvY486_0400570 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TvY486_0029570 ⚠
hypothetical protein, conserved
— OG7
TvY486_0401600 ⚠
hypothetical protein, conserved
— OG7
TvY486_0033450 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_1111570 ⚠
Adaptor protein complex AP-3 subunit beta-3 (
— OG7
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_0302990 ⚠
heat shock protein 90, putative
— OG7
TvY486_1005550 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TvY486_1101900 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_1004540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TvY486_0302010 ⚠
6-phosphofructo-2-kinase 1
— OG7
TvY486_0800510 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TvY486_0100870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TvY486_0603360 ⚠
replication factor C, subunit 2, putative
— OG7
TvY486_1110160 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0905840 ⚠
replication factor C, subunit 3, putative
— OG7
TvY486_1110130 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1010600 ⚠
heat shock protein 83, putative, (fragment)
— +2 more Both
TvY486_0700420
hypothetical protein, conserved
— OG7
TvY486_0601730
hypothetical protein, conserved (fragment)
— Both
TvY486_0801550
mannose-1-phosphate guanyltransferase, putati
— Both
TvY486_0303270 ⚠
heat shock protein, putative
— +2 more Both
TvY486_0503710
dihydrolipoamide branched chain transacylase,
— Both
TvY486_1113650 ⚠
ubiquitin ligase, putative (fragment)
— Both
TvY486_1013850
Histone chaperone Rttp106-like, putative
— Both
TvY486_0402120
hypothetical protein, conserved
— Both
TvY486_0023660 ⚠
lipophosphoglycan biosynthetic protein, putat
— +2 more Both
TvY486_1003780
vacuolar ATP synthase subunit D, putative, (f
— Both
TvY486_1006890
serine peptidase, Clan SC, Family S9B (fragme
— Both
TvY486_0706520 ⚠
ATPase family associated with various cellula
— OG7
TvY486_0023700 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0044030 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_1007860 ⚠
replication factor C subunit 3, putative
— OG7
TvY486_0602010 ⚠
hypothetical protein, conserved
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.