TvY486_0302990

heat shock protein 90, putative

Trypanosoma vivax Y486 OG6: OG6_143062 OG7: OG7_0001978 159 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 159 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_1013570 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_006181 ↔ TCSYLVIO_010666 OG6 Tb927.10.14030 ↔ Tb927.3.3580 OG7 TCSYLVIO_006181 ↔ TCSYLVIO_010666 OG7 Tb927.10.14030 ↔ Tb927.3.3580	Both
TvY486_0802540 ⚠ coronin, putative	—	OG7 Tb927.10.10960 ↔ Tb927.8.3100 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_000174 ↔ TCSYLVIO_009151	OG7
TvY486_0702240 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	OG7
TvY486_0804920 ⚠ tyrosyl/methionyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	OG7
TvY486_1010600 ⚠ heat shock protein 83, putative, (fragment)	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_0023660 ⚠ lipophosphoglycan biosynthetic protein, putat	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_0303270 ⚠ heat shock protein, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_1102710 ⚠ heat shock protein, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_0902180 ⚠ glutamate dehydrogenase, putative	—	OG7 LdBPK_151070.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007064 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007064 ↔ TCSYLVIO_009151 +1 more	OG7
TvY486_1010610 ⚠ heat shock protein 83	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_1010590 ⚠ heat shock protein 83, (fragment)	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_0703520 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	OG7
TvY486_0035480 ⚠ heat shock protein 85, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TvY486_0502690 ⚠ WD domain, G-beta repeat, putative	—	OG6 Tb927.3.3580 ↔ Tb927.5.3260 OG7 Tb927.3.3580 ↔ Tb927.5.3260 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010560 +1 more	Both
TvY486_0601670 ⚠ co-chaperone, putative	—	OG7 TCSYLVIO_003139 ↔ TCSYLVIO_005578	OG7
TvY486_0500500 ⚠ NADH-dependent fumarate reductase, putative	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_009400 +2 more	OG7
TvY486_0901840 ⚠ glutaminyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003355 ↔ TCSYLVIO_005578	OG7
TvY486_0801410 ⚠ glutamyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003355 ↔ TCSYLVIO_005578	OG7
TvY486_0901510 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG7 TCSYLVIO_003428 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009151	OG7
TvY486_0701860 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001150 ↔ TCSYLVIO_005578	OG7
TvY486_1002300 ⚠ vacuolar protein sorting-associated protein 3	—	OG7 LdBPK_210530.1 ↔ LdBPK_332520.1	OG7
TvY486_1009140 ⚠ adenylyl cyclase-associated protein, putative	—	OG7 TCSYLVIO_004711 ↔ TCSYLVIO_005578	OG7
TvY486_1106970 ⚠ hypothetical protein, conserved (fragment)	—	OG7 TCSYLVIO_001673 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_001673 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_001673 ↔ TCSYLVIO_009151	OG7
TvY486_0902090 ⚠ nucleosome assembly protein-like protein, put	—	OG7 TCSYLVIO_007060 ↔ TCSYLVIO_008593 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007060 ↔ TCSYLVIO_009151 +1 more	OG7
TvY486_0501210 ⚠ ribonucleoprotein p18, mitochondrial precurso	—	OG7 TCSYLVIO_002426 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_009151	OG7
TvY486_1006890 ⚠ serine peptidase, Clan SC, Family S9B (fragme	—	OG7 TCSYLVIO_007536 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007536 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007536 ↔ TCSYLVIO_009151	OG7
TvY486_1004010 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005083 ↔ TCSYLVIO_005578	OG7
TvY486_0900810 ⚠ hypothetical protein, conserved (fragment)	—	OG7 TCSYLVIO_003586 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_009151	OG7
TvY486_0804120 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003586 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_009151	OG7
TvY486_1102350 ⚠ phenylalanyl-tRNA synthetase, putative, (frag	—	OG7 TCSYLVIO_005548 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005548 ↔ TCSYLVIO_009151	OG7
TvY486_0801550 ⚠ mannose-1-phosphate guanyltransferase, putati	—	OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009151	OG7
TvY486_1115640 ⚠ Paraflagellar Rod Proteome Component 9, putat	—	OG7 TCSYLVIO_004135 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004135 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004135 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_004135	OG7
TvY486_0014470 ⚠ ubiquitin ligase, putative, (fragment)	—	OG7 TCSYLVIO_006542 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_009151	OG7
TvY486_1111570 ⚠ Adaptor protein complex AP-3 subunit beta-3 (	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009151	OG7
TvY486_0901560 ⚠ heat shock protein, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
TvY486_0402160 ⚠ asparaginyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TvY486_1116920 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TvY486_0906670 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TvY486_1115940 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004111 ↔ TCSYLVIO_011092	OG7
TvY486_1114960 ⚠ phenylalanyl-tRNA synthetase alpha chain, put	—	OG7 TCSYLVIO_004213 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004213 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004213 ↔ TCSYLVIO_009151	OG7
TvY486_0601330 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TvY486_1118010 ⚠ leucine-rich repeat protein (LRRP), putative	—	OG6 TCSYLVIO_005286 ↔ TCSYLVIO_010666 OG7 TCSYLVIO_005286 ↔ TCSYLVIO_010666	Both
TvY486_0013250 ⚠ Possible lysine decarboxylase, putative	—	OG7 TCSYLVIO_002403 ↔ TCSYLVIO_005578	OG7
TvY486_0805800 ⚠ tubulin folding cofactor D, putative, (fragme	—	OG7 TCSYLVIO_001302 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_009151	OG7
TvY486_1009100 ⚠ beta adaptin, putative	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009151	OG7
TvY486_1007920 ⚠ beta adaptin, putative (fragment)	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004597 ↔ TCSYLVIO_009151	OG7
TvY486_0803220 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_008446 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008446 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_008446 ↔ TCSYLVIO_009151	OG7
TvY486_1013850 ⚠ Histone chaperone Rttp106-like, putative	—	OG7 TCSYLVIO_006113 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_006113 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_006113 ↔ TCSYLVIO_009151	OG7
TvY486_1003670 ⚠ NADH-dependent fumarate reductase, putative	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005159 ↔ TCSYLVIO_009400 +2 more	OG7
TvY486_1113650 ⚠ ubiquitin ligase, putative (fragment)	—	OG7 TCSYLVIO_006542 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_009151	OG7

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