TvY486_0805800

tubulin folding cofactor D, putative, (fragment)
Trypanosoma vivax Y486 OG6: OG6_102599 OG7: OG7_0006853 205 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 205 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0802360 ⚠
ribonuclease, putative, (fragment)
— Both
TvY486_0011310 ⚠
ribonuclease, putative, (fragment)
— Both
TvY486_1008230 ⚠
ribonuclease, putative
— Both
TvY486_0600460 ⚠
cysteinyl-tRNA synthetase, putative, (fragmen
— Both
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
TvY486_0100300 ⚠
developmentally regulated phosphoprotein, put
— Both
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— Both
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0601460 ⚠
hypothetical protein, conserved
— Both
TvY486_0400570 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— Both
TvY486_1012540 ⚠
prolyl-tRNA synthetase, putative
— +2 more Both
TvY486_1102350 ⚠
phenylalanyl-tRNA synthetase, putative, (frag
— Both
TvY486_1104860 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TvY486_1015470 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_0010920 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0100870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TvY486_0603360 ⚠
replication factor C, subunit 2, putative
— OG7
TvY486_1110160 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0905840 ⚠
replication factor C, subunit 3, putative
— OG7
TvY486_1110130 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1008260 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0602010 ⚠
hypothetical protein, conserved
— OG7
TvY486_0706520 ⚠
ATPase family associated with various cellula
— OG7
TvY486_0044030 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0023700 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_1007860 ⚠
replication factor C subunit 3, putative
— OG7
TvY486_0501210 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TvY486_0701430 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TvY486_1013190 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
TvY486_0700470 ⚠
heat shock 70 kDa protein, putative
— OG6
TvY486_0602450 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TvY486_1104110 ⚠
AMP deaminase, putative, (fragment)
— Both
TvY486_0801550 ⚠
mannose-1-phosphate guanyltransferase, putati
— Both
TvY486_0906210 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
TvY486_0404030 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0303270 ⚠
heat shock protein, putative
— +2 more Both
TvY486_0503710 ⚠
dihydrolipoamide branched chain transacylase,
— Both
TvY486_0030700 ⚠
glucose-regulated protein 78, putative
— OG6
TvY486_1113650 ⚠
ubiquitin ligase, putative (fragment)
— Both
TvY486_1013850 ⚠
Histone chaperone Rttp106-like, putative
— Both
TvY486_0402120 ⚠
hypothetical protein, conserved
— Both
TvY486_0023660 ⚠
lipophosphoglycan biosynthetic protein, putat
— +2 more Both
TvY486_0100940 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
TvY486_0305030 ⚠
Metallopeptidase family M24/FACT complex subu
— Both
TvY486_1112290 ⚠
heat shock protein 70, putative, (fragment)
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.