TvY486_0701430

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma vivax Y486 OG6: OG6_132778 OG7: OG7_0002306 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1010810 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1004470 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TvY486_0906210 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0501140 ⚠
protein kinase, putative, serine/threonine-pr
— OG7
TvY486_0004430 ⚠
ATP synthase (E/31 kDa) subunit, putative
— OG7
TvY486_0301680 ⚠
COP9 signalosome complex subunit 2, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_1000630 ⚠
2-oxoisovalerate dehydrogenase, putative
— OG7
TvY486_1101330 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TvY486_0302990 ⚠
heat shock protein 90, putative
— OG7
TvY486_1015470 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_0903690 ⚠
isopentenyl-diphosphate delta-isomerase (type
— OG7
TvY486_1111570 ⚠
Adaptor protein complex AP-3 subunit beta-3 (
— OG7
TvY486_1000720 ⚠
ATP synthase, putative
— OG7
TvY486_1004950 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TvY486_1000010 ⚠
ATP synthase, putative
— OG7
TvY486_0033450 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_1012540 ⚠
prolyl-tRNA synthetase, putative
— OG7
TvY486_0401600 ⚠
hypothetical protein, conserved
— OG7
TvY486_0005790 ⚠
ATP synthase, putative
— OG7
TvY486_1001290 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TvY486_0304720 ⚠
Hsc70-interacting protein (Hip), putative
— OG7
TvY486_1110800 ⚠
vacuolar sorting-associated protein-like, put
— OG7
TvY486_0703870 ⚠
protein kinase, putative, (fragment)
— OG7
TvY486_0029570 ⚠
hypothetical protein, conserved
— OG7
TvY486_0036220 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_0400570 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TvY486_1013570 ⚠
hypothetical protein, conserved
— OG7
TvY486_0704120 ⚠
serine/threonine-protein kinase, putative
— OG7
TvY486_0008090 ⚠
ATP synthase, putative (fragment)
— OG7
TvY486_1009320 ⚠
branch point binding protein, putative
— OG7
TvY486_0027600 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
TvY486_1111650 ⚠
vacuolar sorting-associated protein-like, put
— OG7
TvY486_0020590 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_1102710 ⚠
heat shock protein, putative
— OG7
TvY486_1105670 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TvY486_0904770 ⚠
synaptojanin (N-terminal domain), putative, (
— OG7
TvY486_0603300 ⚠
hypothetical protein, conserved
— OG7
TvY486_1004520 ⚠
PUB domain containing protein, putative
— OG7
TvY486_1108460 ⚠
oxidoreductase-like protein, putative
— OG7
TvY486_0503800 ⚠
hypothetical protein, conserved
— OG7
TvY486_1013840 ⚠
Hsp70 protein, putative
— OG7
TvY486_1115330 ⚠
G5-interacting protein, putative
— OG7
TvY486_0704910 ⚠
hypothetical protein, conserved
— OG7
TvY486_1116740 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1109460 ⚠
HERTS, (fragment)
— OG7
TvY486_0201932 ⚠
hypothetical protein, conserved
— OG7
TvY486_0807150 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.