TvY486_1012540

prolyl-tRNA synthetase, putative

Trypanosoma vivax Y486 OG6: OG6_100749 OG7: OG7_0002333 191 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 191 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_1013570 hypothetical protein, conserved	—	OG6 LdBPK_180550.1 ↔ LdBPK_181230.1 OG6 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 LdBPK_180550.1 ↔ LdBPK_181230.1	Both
TvY486_0600460 cysteinyl-tRNA synthetase, putative, (fragmen	—	OG6 LdBPK_120255.1 ↔ LdBPK_181220.1 OG6 LdBPK_120255.1 ↔ LdBPK_181230.1 OG6 Tb927.10.12890 ↔ Tb927.6.950 OG7 Tb927.10.12890 ↔ Tb927.6.950 +2 more	Both
TvY486_0702440 ⚠ guide RNA associated protein, GAP2	—	OG6 LdBPK_181230.1 ↔ LdBPK_220520.1 OG6 TCSYLVIO_001262 ↔ TCSYLVIO_006246 OG7 LdBPK_181230.1 ↔ LdBPK_220520.1 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_006246	Both
TvY486_0805800 ⚠ tubulin folding cofactor D, putative, (fragme	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
TvY486_1103120 ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_005619 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_006246	Both
TvY486_0702420 ⚠ guide RNA associated protein, GAP2	—	OG6 LdBPK_181230.1 ↔ LdBPK_220520.1 OG6 TCSYLVIO_001262 ↔ TCSYLVIO_006246 OG7 LdBPK_181230.1 ↔ LdBPK_220520.1 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_006246	Both
TvY486_1012470 hypothetical protein, conserved	—	OG6 TCSYLVIO_006238 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 TCSYLVIO_006238 ↔ TCSYLVIO_006246	Both
TvY486_0032470 ⚠ hypothetical protein, conserved in T. vivax	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246	OG6
TvY486_0402160 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_342110.1 OG6 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 +1 more	Both
TvY486_0601330 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
TvY486_1114840 ⚠ Outer row dynein-assembly protein 7	—	OG7 LdBPK_181220.1 ↔ LdBPK_261200.1 OG7 LdBPK_181230.1 ↔ LdBPK_261200.1	OG7
TvY486_0901110 ⚠ u6 snrna-associated sm-like protein, Sm- like	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
TvY486_0601670 co-chaperone, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300770.1	OG7
TvY486_1015470 ⚠ Eukaryotic translation initiation factor 4E-2	—	OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	OG7
TvY486_0010920 ⚠ hypothetical protein, conserved (fragment)	—	OG7 LdBPK_181220.1 ↔ LdBPK_261200.1 OG7 LdBPK_181230.1 ↔ LdBPK_261200.1	OG7
TvY486_0305050 ⚠ nuclear transcription factor, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_220007.1 OG7 LdBPK_181230.1 ↔ LdBPK_220007.1	OG7
TvY486_0400030 ⚠ hypothetical protein, conserved (fragment)	—	OG7 LdBPK_181230.1 ↔ LdBPK_300970.1 OG7 LdBPK_161180.1 ↔ LdBPK_181220.1 OG7 LdBPK_161180.1 ↔ LdBPK_181230.1	OG7
TvY486_0023700 ⚠ replication factor C, subunit 4, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
TvY486_1007860 ⚠ replication factor C subunit 3, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
TvY486_0602010 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_181230.1 ↔ LdBPK_300970.1 OG7 LdBPK_161180.1 ↔ LdBPK_181220.1 OG7 LdBPK_161180.1 ↔ LdBPK_181230.1	OG7
TvY486_1115100 ⚠ small nuclear ribonucleoprotein Sm-G	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
TvY486_1102510 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 LdBPK_110640.1 ↔ LdBPK_181220.1 OG7 LdBPK_110640.1 ↔ LdBPK_181230.1	OG7
TvY486_0706750 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
TvY486_1004950 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
TvY486_1101330 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
TvY486_1104110 AMP deaminase, putative, (fragment)	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_006246	Both
TvY486_1013190 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_006138 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	Both
TY486_1009410 leucine-rich repeat protein (LRRP), putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006246	Both
TvY486_0200266 hypothetical protein, conserved (fragment)	—	OG6 LdBPK_020280.1 ↔ LdBPK_181220.1 OG6 LdBPK_020280.1 ↔ LdBPK_181230.1 OG7 LdBPK_020280.1 ↔ LdBPK_181220.1 OG7 LdBPK_020280.1 ↔ LdBPK_181230.1	Both
TvY486_0021890 ⚠ hypothetical protein (fragment)	—	OG6 LdBPK_181230.1 ↔ LdBPK_321150.1 OG7 LdBPK_181230.1 ↔ LdBPK_321150.1	Both
TvY486_0501510 ⚠ GMP reductase	—	OG6 LdBPK_181220.1 ↔ LdBPK_191590.1 OG6 LdBPK_181230.1 ↔ LdBPK_191590.1	OG6
TvY486_0009670 hypothetical protein, conserved (fragment)	—	OG6 LdBPK_181220.1 ↔ LdBPK_331980.1 OG6 LdBPK_181230.1 ↔ LdBPK_331980.1 OG7 LdBPK_181220.1 ↔ LdBPK_331980.1 OG7 LdBPK_181230.1 ↔ LdBPK_331980.1	Both
TvY486_0907250 casein kinase II, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_351720.1 OG6 LdBPK_181230.1 ↔ LdBPK_351720.1	OG6
TvY486_0700160 ⚠ protein farnesyltransferase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_261450.1 OG6 LdBPK_181230.1 ↔ LdBPK_261450.1 OG7 LdBPK_181220.1 ↔ LdBPK_261450.1 OG7 LdBPK_181230.1 ↔ LdBPK_261450.1	Both
TvY486_1102350 phenylalanyl-tRNA synthetase, putative, (frag	—	OG6 LdBPK_181220.1 ↔ LdBPK_191010.1 OG6 LdBPK_181230.1 ↔ LdBPK_191010.1 OG7 LdBPK_181220.1 ↔ LdBPK_191010.1 OG7 LdBPK_181230.1 ↔ LdBPK_191010.1	Both
TvY486_1010650 DNA mismatch repair protein MSH2, putative (f	—	OG6 LdBPK_181230.1 ↔ LdBPK_330420.1 OG7 LdBPK_181230.1 ↔ LdBPK_330420.1	Both
TvY486_0040320 ⚠ hypothetical protein, conserved in T. vivax	—	OG6 LdBPK_181230.1 ↔ LdBPK_321150.1	OG6
TvY486_0302660 protein kinase, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_292600.1 OG7 LdBPK_181230.1 ↔ LdBPK_292600.1	Both
TvY486_0905890 hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_353250.1 OG6 LdBPK_181230.1 ↔ LdBPK_353250.1 OG7 LdBPK_181220.1 ↔ LdBPK_353250.1 OG7 LdBPK_181230.1 ↔ LdBPK_353250.1	Both
TvY486_0700500 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_261200.1 OG6 LdBPK_181230.1 ↔ LdBPK_261200.1 OG7 LdBPK_181220.1 ↔ LdBPK_261200.1 OG7 LdBPK_181230.1 ↔ LdBPK_261200.1	Both
TvY486_1106730 ⚠ hypothetical protein, conserved (fragment)	—	OG6 LdBPK_110920.1 ↔ LdBPK_181220.1 OG6 LdBPK_110920.1 ↔ LdBPK_181230.1 OG7 LdBPK_110920.1 ↔ LdBPK_181220.1 OG7 LdBPK_110920.1 ↔ LdBPK_181230.1	Both
TvY486_1106760 hypothetical protein, conserved	—	OG6 LdBPK_110890.1 ↔ LdBPK_181220.1 OG6 LdBPK_110890.1 ↔ LdBPK_181230.1 OG7 LdBPK_110890.1 ↔ LdBPK_181220.1 OG7 LdBPK_110890.1 ↔ LdBPK_181230.1	Both
TvY486_0901510 DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006246	Both
TvY486_0502690 WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_181220.1 OG6 LdBPK_080420.1 ↔ LdBPK_181230.1 OG7 LdBPK_080420.1 ↔ LdBPK_181220.1 OG7 LdBPK_080420.1 ↔ LdBPK_181230.1	Both
TvY486_0101620 ⚠ Centrosomal protein of 164 kDa, putative	—	OG6 LdBPK_120470.1 ↔ LdBPK_181220.1 OG6 LdBPK_120470.1 ↔ LdBPK_181230.1 OG7 LdBPK_120470.1 ↔ LdBPK_181220.1 OG7 LdBPK_120470.1 ↔ LdBPK_181230.1	Both
TvY486_0404030 ⚠ hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_002919 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_002919 ↔ TCSYLVIO_006246	Both
TvY486_0702380 Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_006246	Both
TvY486_0807150 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002919 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_002919 ↔ TCSYLVIO_006246	Both
TvY486_0602200 hypothetical protein, conserved	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_006246	Both
TvY486_1109330 ⚠ hypothetical protein, conserved (fragment)	—	OG6 LdBPK_110920.1 ↔ LdBPK_181220.1 OG6 LdBPK_110920.1 ↔ LdBPK_181230.1 OG7 LdBPK_110920.1 ↔ LdBPK_181220.1 OG7 LdBPK_110920.1 ↔ LdBPK_181230.1	Both

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