TvY486_0501510

GMP reductase
Trypanosoma vivax Y486 OG6: OG6_100534 OG7: OG7_0002928 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0002690 ⚠
dihydrolipoamide dehydrogenase, putative
— OG6
TvY486_1012540 ⚠
prolyl-tRNA synthetase, putative
— OG6
TvY486_1116870 ⚠
prefoldin subunit, putative
— OG6
TvY486_1101600 ⚠
cysteine desulfurase, putative
— Both
TvY486_1109330 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_1106730 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— OG6
TvY486_1106990 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG6
TvY486_0804580 ⚠
EMG1/NEP1 methyltransferase, putative
— Both
TvY486_1006840 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
TvY486_0500420 ⚠
Nucleolar protein 111, putative
— Both
TvY486_1004305 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— OG6
TvY486_0300760 ⚠
ATP synthase subunit beta, mitochondrial, put
— OG6
TvY486_0806860 ⚠
acetoin dehydrogenase e3 component, putative,
— OG6
TvY486_0500560 ⚠
hypothetical protein, conserved
— Both
TvY486_1013110 ⚠
Zn-finger in Ran binding protein and others/F
— OG6
TvY486_0009080 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— OG6
TvY486_0700010 ⚠
ribosome biogenesis protein, putative
— Both
TvY486_0907400 ⚠
rRNA processing protein, putative
— Both
TvY486_0603710 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG6
TvY486_0601540 ⚠
ribosome biogenesis regulatory protein (RRS1)
— Both
TvY486_0302130 ⚠
peter pan protein, putative, (fragment)
— Both
TvY486_1106760 ⚠
hypothetical protein, conserved
— OG6
TvY486_0200266 ⚠
hypothetical protein, conserved (fragment)
— OG6
TvY486_1101360 ⚠
hypothetical protein, conserved
— Both
TvY486_1114860 ⚠
nuclear RNA binding domain
— Both
TvY486_1114210 ⚠
hypothetical protein, conserved
— OG6
TvY486_0705460 ⚠
hypothetical protein, conserved
— OG6
TvY486_0201570 ⚠
EMG1/NEP1 methyltransferase, putative
— OG7
TvY486_0801910 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG6
TvY486_1101380 ⚠
hypothetical protein, conserved
— Both
TvY486_0300730 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_1109550 ⚠
p21-C-terminal region-binding protein, putati
— OG6
TvY486_0201934 ⚠
hypothetical protein, conserved
— OG6
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG6
TvY486_0700930 ⚠
hypothetical protein, conserved
— OG6
TvY486_0200880 ⚠
translation initiation factor IF-2, putative
— OG6
TvY486_0021110 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG6
TvY486_0100350 ⚠
ARM-like helical domain-containing protein
— OG6
TvY486_1004320 ⚠
hypothetical protein, conserved
— OG6
TvY486_1001290 ⚠
Domain of unknown function (DUF4042), putativ
— OG6
TvY486_0701770 ⚠
R3H domain containing protein, putative
— OG6
TvY486_0601460 ⚠
hypothetical protein, conserved
— OG6
TvY486_0602580 ⚠
microtubule associated protein xmap215
— OG6
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
TvY486_0907250 ⚠
casein kinase II, putative
— OG6
TvY486_0700160 ⚠
protein farnesyltransferase, putative
— OG6
TvY486_0201932 ⚠
hypothetical protein, conserved
— OG6
TvY486_0905890 ⚠
hypothetical protein, conserved
— OG6
TvY486_1102915 ⚠
hypothetical protein, conserved (fragment)
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.