TY486_1009410

leucine-rich repeat protein (LRRP), putative

Trypanosoma vivax Y486 OG6: OG6_110710 OG7: OG7_0006349 149 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 149 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_0800510 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG6 TCSYLVIO_004468 ↔ TCSYLVIO_004736 OG6 LdBPK_030790.1 ↔ LdBPK_364440.1 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_004468 ↔ TCSYLVIO_004736	Both
TvY486_0302010 ⚠ 6-phosphofructo-2-kinase 1	—	OG6 TCSYLVIO_004468 ↔ TCSYLVIO_004736 OG6 LdBPK_030790.1 ↔ LdBPK_364440.1 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_004468 ↔ TCSYLVIO_004736	Both
TvY486_0906210 ⚠ Leucine carboxyl methyltransferase/Cupin-like	—	OG6 LdBPK_352990.1 ↔ LdBPK_364440.1 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005852	Both
TvY486_1102350 phenylalanyl-tRNA synthetase, putative, (frag	—	OG6 LdBPK_191010.1 ↔ LdBPK_364440.1 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005548	Both
TvY486_0601330 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004736	Both
TvY486_1000630 2-oxoisovalerate dehydrogenase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009339 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009339	Both
TvY486_0500690 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007511 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007511	Both
TvY486_0600460 cysteinyl-tRNA synthetase, putative, (fragmen	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006977	Both
TvY486_0503220 ubiquitin-activating enzyme E1, putative, (fr	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010542	Both
TvY486_1000720 ATP synthase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009332 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009332	Both
TvY486_0803220 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008446 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008446	Both
TvY486_0803110 exonuclease, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010944	Both
TvY486_1000010 ⚠ ATP synthase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009199	Both
TvY486_0500500 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005116 +2 more	Both
TvY486_1012540 prolyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006246	Both
TvY486_0402580 Zeta toxin, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010958 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010958	Both
TvY486_0028470 ⚠ hypothetical protein, conserved in T. vivax,	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008446	OG6
TvY486_0005790 ⚠ ATP synthase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009199	Both
TvY486_0304720 Hsc70-interacting protein (Hip), putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010703 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010703	Both
TvY486_0036220 ⚠ hypothetical protein, conserved in T. vivax (	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009199	Both
TvY486_1003670 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005116 +2 more	Both
TvY486_1000090 ⚠ ATP synthase F1 subunit gamma	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009375	Both
TvY486_0905690 hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005810 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005810	Both
TvY486_1013570 hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006181 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006181	Both
TvY486_1116920 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005374 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005374	Both
TvY486_0008090 ⚠ ATP synthase, putative (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009199	Both
TvY486_0801550 mannose-1-phosphate guanyltransferase, putati	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007603	Both
TvY486_0303270 ⚠ heat shock protein, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0503710 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009880	Both
TvY486_1113650 ⚠ ubiquitin ligase, putative (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006542 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006542	Both
TvY486_1013850 Histone chaperone Rttp106-like, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006113 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006113	Both
TvY486_0023660 ⚠ lipophosphoglycan biosynthetic protein, putat	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_1003780 vacuolar ATP synthase subunit D, putative, (f	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005104 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005104	Both
TvY486_1006890 serine peptidase, Clan SC, Family S9B (fragme	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007536	Both
TvY486_0502690 WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010560	Both
TvY486_1010600 ⚠ heat shock protein 83, putative, (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0305030 Metallopeptidase family M24/FACT complex subu	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010728	Both
TvY486_0100940 ⚠ calpain-like cysteine peptidase, putative, cy	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007342	OG6
TvY486_1014300 C-terminal motor kinesin, putative, (fragment	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006065	OG6
TvY486_1012470 hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006238 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006238	Both
TvY486_0020590 ⚠ hypothetical protein, conserved in T.vivax	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006596 OG7 TCSYLVIO_000702 ↔ TCSYLVIO_004736	OG7
TvY486_0028820 ⚠ hypothetical protein, conserved in T.vivax	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006596 OG7 TCSYLVIO_000702 ↔ TCSYLVIO_004736	OG7
TvY486_0904770 ⚠ synaptojanin (N-terminal domain), putative, (	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007569	OG7
TvY486_1105670 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007569	OG7
TvY486_1102710 ⚠ heat shock protein, putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009151	OG7
TvY486_0704120 ⚠ serine/threonine-protein kinase, putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009362	OG7
TvY486_0029570 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007569	OG7
TvY486_0400570 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_004736	OG7
TvY486_0906670 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005374	OG7
TvY486_0027600 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007569	OG7

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