TvY486_0800510

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma vivax Y486 OG6: OG6_100250 OG7: OG7_0002306 166 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 166 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1010810 ⚠
hypothetical protein, conserved (fragment)
— Both
TY486_1009410 ⚠
leucine-rich repeat protein (LRRP), putative
— Both
TvY486_0906210 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
TvY486_1004470 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TvY486_0704120 ⚠
serine/threonine-protein kinase, putative
— OG7
TvY486_0400350 ⚠
GRIP domain containing protein, putative
— OG7
TvY486_1009430 ⚠
serine/threonine kinase, putative
— OG7
TvY486_1104870 ⚠
clathrin coat assembly protein, putative
— OG7
TvY486_1010590 ⚠
heat shock protein 83, (fragment)
— OG7
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TvY486_0601320 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TvY486_1005550 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TvY486_0023570 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
TvY486_1103210 ⚠
dual-specificity protein kinase, putative
— OG7
TvY486_1010610 ⚠
heat shock protein 83
— OG7
TvY486_1114960 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
TvY486_0501140 ⚠
protein kinase, putative, serine/threonine-pr
— OG7
TvY486_0014470 ⚠
ubiquitin ligase, putative, (fragment)
— OG7
TvY486_0100300 ⚠
developmentally regulated phosphoprotein, put
— OG7
TvY486_0801700 ⚠
pteridine reductase 1
— OG7
TvY486_1101330 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TvY486_0302990 ⚠
heat shock protein 90, putative
— OG7
TvY486_1015470 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TvY486_0500690 ⚠
threonyl-tRNA synthetase, putative
— OG7
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_1007920 ⚠
beta adaptin, putative (fragment)
— OG7
TvY486_0400180 ⚠
snoRNP protein GAR1, putative
— OG7
TvY486_0600460 ⚠
cysteinyl-tRNA synthetase, putative, (fragmen
— OG7
TvY486_0503220 ⚠
ubiquitin-activating enzyme E1, putative, (fr
— OG7
TvY486_1111570 ⚠
Adaptor protein complex AP-3 subunit beta-3 (
— OG7
TvY486_1104860 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TvY486_1004950 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TvY486_0803110 ⚠
exonuclease, putative
— OG7
TvY486_0033450 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_0402580 ⚠
Zeta toxin, putative
— OG7
TvY486_0401600 ⚠
hypothetical protein, conserved
— OG7
TvY486_0900810 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0703870 ⚠
protein kinase, putative, (fragment)
— OG7
TvY486_0029570 ⚠
hypothetical protein, conserved
— OG7
TvY486_0400570 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TvY486_1000090 ⚠
ATP synthase F1 subunit gamma
— OG7
TvY486_0905690 ⚠
hypothetical protein, conserved
— OG7
TvY486_1116920 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_0804120 ⚠
hypothetical protein, conserved
— OG7
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0802360 ⚠
ribonuclease, putative, (fragment)
— OG7
TvY486_0011310 ⚠
ribonuclease, putative, (fragment)
— OG7
TvY486_1008230 ⚠
ribonuclease, putative
— OG7
TvY486_1015010 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TvY486_0701280 ⚠
pseudouridylate synthase I, putative, (fragme
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.