TvY486_0400570

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative
Trypanosoma vivax Y486 OG6: OG6_146732 OG7: OG7_0002830 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1102350 ⚠
phenylalanyl-tRNA synthetase, putative, (frag
— OG7
TvY486_0600460 ⚠
cysteinyl-tRNA synthetase, putative, (fragmen
— OG7
TvY486_0100300 ⚠
developmentally regulated phosphoprotein, put
— OG7
TvY486_1104860 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TvY486_1008230 ⚠
ribonuclease, putative
— OG7
TvY486_0802360 ⚠
ribonuclease, putative, (fragment)
— OG7
TvY486_0011310 ⚠
ribonuclease, putative, (fragment)
— OG7
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0805800 ⚠
tubulin folding cofactor D, putative, (fragme
— OG7
TvY486_0021110 ⚠
aspartyl aminopeptidase, putative (fragment)
— OG7
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_0801000 ⚠
hypothetical protein, conserved
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— +1 more OG7
TvY486_0035480 ⚠
heat shock protein 85, putative
— +2 more OG7
TvY486_0703300 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TvY486_0014050 ⚠
heat shock protein 70, putative, (fragment)
— OG7
TvY486_0400350 ⚠
GRIP domain containing protein, putative
— OG7
TvY486_0905790 ⚠
hypothetical protein, conserved
— OG7
TvY486_1010590 ⚠
heat shock protein 83, (fragment)
— +2 more OG7
TvY486_0006090 ⚠
peptidylprolyl isomerase-like, putative (frag
— OG7
TvY486_0037920 ⚠
heat shock 70 kDa protein, mitochondrial prec
— OG7
TvY486_1005550 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TvY486_0023570 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
TvY486_1108460 ⚠
oxidoreductase-like protein, putative
— OG7
TvY486_1010610 ⚠
heat shock protein 83
— +2 more OG7
TvY486_1014960 ⚠
macrophage infectivity potentiator, precursor
— OG7
TvY486_1112330 ⚠
heat shock protein 70, putative
— OG7
TvY486_0700860 ⚠
heat shock 70 kDa protein, putative
— OG7
TvY486_1004640 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TvY486_0801700 ⚠
pteridine reductase 1
— OG7
TvY486_0302990 ⚠
heat shock protein 90, putative
— +2 more OG7
TvY486_1014970 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TvY486_0500690 ⚠
threonyl-tRNA synthetase, putative
— OG7
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_1007920 ⚠
beta adaptin, putative (fragment)
— OG7
TvY486_0503220 ⚠
ubiquitin-activating enzyme E1, putative, (fr
— OG7
TvY486_1111570 ⚠
Adaptor protein complex AP-3 subunit beta-3 (
— OG7
TvY486_0803220 ⚠
hypothetical protein, conserved
— OG7
TvY486_0803110 ⚠
exonuclease, putative
— OG7
TvY486_0025780 ⚠
heat shock protein 70, putative (fragment)
— OG7
TvY486_0401600 ⚠
hypothetical protein, conserved
— OG7
TvY486_0402580 ⚠
Zeta toxin, putative
— OG7
TvY486_0900810 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0705530 ⚠
protein arginine n-methyltransferase 7 (fragm
— OG7
TvY486_0021490 ⚠
heat shock protein 70-related protein
— OG7
TvY486_1006890 ⚠
serine peptidase, Clan SC, Family S9B (fragme
— OG7
TvY486_0904320 ⚠
Hsp70 protein, putative
— OG7
TvY486_0403110 ⚠
uracil phosphoribosyltransferase, putative, (
— OG7
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.