TvY486_0400350

GRIP domain containing protein, putative
Trypanosoma vivax Y486 OG6: OG6_147115 OG7: OG7_0043222 244 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 244 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1111570 ⚠
Adaptor protein complex AP-3 subunit beta-3 (
— Both
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_0906670 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_1007920 ⚠
beta adaptin, putative (fragment)
— Both
TvY486_1101900 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_1116920 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TvY486_1103090 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— OG7
TvY486_1007300 ⚠
cullin, putative
— OG7
TvY486_1112430 ⚠
cullin 2, putative
— OG7
TvY486_0300300
hypothetical protein, conserved
— OG7
TvY486_1013420 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TvY486_0304760 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TvY486_0201820 ⚠
tubulin-tyrosine ligase, putative, (fragment)
— OG7
TvY486_0904090 ⚠
tubulin tyrosine ligase, putative
— OG7
TvY486_1107160 ⚠
tubulin-tyrsoine ligase-like protein, putativ
— OG7
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0603060 ⚠
tubulin-tyrosine ligase-like protein, conserv
— OG7
TvY486_0100690 ⚠
tubulin-tyrosine ligase, putative
— OG7
TvY486_1105760 ⚠
DNA replication licensing factor, putative, (
— OG7
TvY486_0904100 ⚠
DNA replication factor, putative
— OG7
TvY486_0200950 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_1116980 ⚠
DNA replication licensing factor, putative
— OG7
TvY486_1112670 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_1113210 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
TvY486_1004540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TvY486_0302010 ⚠
6-phosphofructo-2-kinase 1
— OG7
TvY486_0800510 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1008260 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0804880 ⚠
WW domain containing protein, putative
— OG7
TvY486_1008940
hypothetical protein, conserved
— Both
TvY486_0601460
hypothetical protein, conserved
— Both
TvY486_1109470
hypothetical protein, conserved
— Both
TvY486_1013780
Flagellum attachment zone protein 9
— Both
TvY486_1006440
hypothetical protein, conserved
— Both
TvY486_1007080
Flagellar Member 1 (fragment)
— Both
TvY486_1111370
PQQ-like domain/WD domain, G-beta repeat/Utp2
— Both
TvY486_1111940
2OG-Fe(II) oxygenase superfamily, putative
— Both
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_0502575 ⚠
ribose-phosphate pyrophosphokinase, putative,
— Both
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— Both
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— Both
TvY486_0805800 ⚠
tubulin folding cofactor D, putative, (fragme
— Both
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_0905610
acyl transferase-like protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.