TvY486_1111570

Adaptor protein complex AP-3 subunit beta-3 (fragment)
Trypanosoma vivax Y486 OG6: OG6_101595 OG7: OG7_0001921 211 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 211 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0400350 ⚠
GRIP domain containing protein, putative
— Both
TvY486_1115360 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TvY486_0400570 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TvY486_1104860 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TvY486_0100300 ⚠
developmentally regulated phosphoprotein, put
— OG7
TvY486_0700650 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0020590 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0033450 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_0901510 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TvY486_1115410 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TvY486_0100900 ⚠
phosphatidylinositol 3-kinase, putative, (fra
— OG7
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TvY486_1008310 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TvY486_0200350 ⚠
phosphatidylinositol kinase domain protein, p
— OG7
TvY486_1013110 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
TvY486_0024850 ⚠
hypothetical protein, conserved in T. vivax
— OG7
TvY486_0029580 ⚠
hypothetical protein
— OG7
TvY486_0700445 ⚠
zinc finger protein, putative
— OG7
TvY486_0703750 ⚠
hypothetical protein, conserved
— OG7
TvY486_0701710 ⚠
hypothetical protein, conserved
— OG7
TvY486_1106970 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0905580 ⚠
predicted zinc finger protein, zinc finger pr
— OG7
TvY486_0903390 ⚠
adenylate kinase, putative
— OG7
TvY486_0802540 ⚠
coronin, putative
— OG7
TvY486_1004350 ⚠
adenylate kinase, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_0806890 ⚠
RNA polymerase IIA largest subunit, (fragment
— OG7
TvY486_0300300 ⚠
hypothetical protein, conserved
— OG7
TvY486_1112430 ⚠
cullin 2, putative
— OG7
TvY486_1007300 ⚠
cullin, putative
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— OG7
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_0805490 ⚠
cullin, putative
— OG7
TvY486_1006870 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TvY486_0013050 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0404370 ⚠
RNA polymerase IIA largest subunit, (fragment
— OG7
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— OG7
TvY486_1107690 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_1107670 ⚠
neurobeachin/beige protein, putative
— OG7
TvY486_0802790 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TvY486_1114960 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TvY486_0805930 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— OG7
TvY486_0400180 ⚠
snoRNP protein GAR1, putative
— OG7
TvY486_0200840 ⚠
hypothetical protein, conserved (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.