TvY486_0806890

RNA polymerase IIA largest subunit, (fragment)
Trypanosoma vivax Y486 OG6: OG6_100210 OG7: OG7_0001854 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1014740 ⚠
DNA-directed RNA polymerases I and III subuni
— +2 more Both
TvY486_0502330 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
TvY486_0806620 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TvY486_0502575 ⚠
ribose-phosphate pyrophosphokinase, putative,
— Both
TvY486_0304910 ⚠
DNA-directed RNA polymerase II subunit 3, put
— +1 more Both
TvY486_0403520 ⚠
DNA-directed RNA polymerase II subunit 2, put
— +4 more Both
TvY486_0100010 ⚠
DNA-directed RNA polymerase III, putative (fr
— +4 more Both
TvY486_1100480 ⚠
RNA polymerase I second largest subunit, puta
— +1 more OG7
TvY486_1009350 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TvY486_1103090 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TvY486_0804650 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TvY486_1107080 ⚠
pumilio-repeat, RNA-binding protein, putative
— OG7
TvY486_1117890 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
TvY486_1112670 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_0601080 ⚠
hypothetical protein, conserved
— OG7
TvY486_0300660 ⚠
PRP38 family, putative
— OG7
TvY486_0500840 ⚠
exosome component CSL4, putative
— OG7
TvY486_1008310 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TvY486_0703750 ⚠
hypothetical protein, conserved
— OG7
TvY486_0807380 ⚠
hypothetical protein, conserved
— OG7
TvY486_1111370 ⚠
PQQ-like domain/WD domain, G-beta repeat/Utp2
— OG7
TvY486_1116980 ⚠
DNA replication licensing factor, putative
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— OG7
TvY486_1101350 ⚠
Right handed beta helix region/Periplasmic co
— OG7
TvY486_1013780 ⚠
Flagellum attachment zone protein 9
— OG7
TvY486_1108600 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_1114830 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0700445 ⚠
zinc finger protein, putative
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_1109470 ⚠
hypothetical protein, conserved
— OG7
TvY486_0906610 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0706700 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TvY486_0100900 ⚠
phosphatidylinositol 3-kinase, putative, (fra
— OG7
TvY486_0200840 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0701174 ⚠
hypothetical protein, conserved
— OG7
TvY486_1105960 ⚠
formin-like protein
— OG7
TvY486_0029580 ⚠
hypothetical protein
— OG7
TvY486_1007080 ⚠
Flagellar Member 1 (fragment)
— OG7
TvY486_0705180 ⚠
SpoU rRNA Methylase family, putative
— OG7
TvY486_0200950 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_0402270 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TvY486_0700650 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1100210 ⚠
RNA-binding protein, putative (fragment)
— OG7
TvY486_0024850 ⚠
hypothetical protein, conserved in T. vivax
— OG7
TvY486_1006120 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_1006440 ⚠
hypothetical protein, conserved
— OG7
TvY486_1104040 ⚠
hypothetical protein, conserved
— OG7
TvY486_0101190 ⚠
histone H3, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.