TvY486_0500840

exosome component CSL4, putative
Trypanosoma vivax Y486 OG6: OG6_141889 OG7: OG7_0006954 152 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 152 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0902710
exosome complex exonuclease RRP40, putative
— Both
TvY486_1100480 ⚠
RNA polymerase I second largest subunit, puta
— Both
TvY486_0403520 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TvY486_0002850 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0807380 ⚠
hypothetical protein, conserved
— Both
TvY486_0100010 ⚠
DNA-directed RNA polymerase III, putative (fr
— OG7
TvY486_0904090 ⚠
tubulin tyrosine ligase, putative
— OG7
TvY486_0021490 ⚠
heat shock protein 70-related protein
— Both
TvY486_1112290 ⚠
heat shock protein 70, putative, (fragment)
— OG6
TvY486_1112430 ⚠
cullin 2, putative
— OG7
TvY486_0300300
hypothetical protein, conserved
— OG7
TvY486_0806860 ⚠
acetoin dehydrogenase e3 component, putative,
— OG7
TvY486_0200350 ⚠
phosphatidylinositol kinase domain protein, p
— OG7
TvY486_1005090 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TvY486_0703580 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TvY486_1113210 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_1007920 ⚠
beta adaptin, putative (fragment)
— OG7
TvY486_1113870 ⚠
polyubiquitin, putative
— OG7
TvY486_0501680 ⚠
formin, putative
— OG7
TvY486_1007300 ⚠
cullin, putative
— OG7
TvY486_1110600 ⚠
polyubiquitin, putative
— OG7
TvY486_0002690 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TvY486_1112670 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_1008310 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— OG7
TvY486_1116980 ⚠
DNA replication licensing factor, putative
— OG7
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TvY486_0100900 ⚠
phosphatidylinositol 3-kinase, putative, (fra
— OG7
TvY486_0705180 ⚠
SpoU rRNA Methylase family, putative
— OG7
TvY486_0200950 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
TvY486_0805490 ⚠
cullin, putative
— OG7
TvY486_1115410 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TvY486_1006870 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TvY486_0904100 ⚠
DNA replication factor, putative
— OG7
TvY486_1105760 ⚠
DNA replication licensing factor, putative, (
— OG7
TvY486_0200268 ⚠
ribosomal RNA processing protein 41B, putativ
— OG7
TvY486_0100690 ⚠
tubulin-tyrosine ligase, putative
— OG7
TvY486_0603060 ⚠
tubulin-tyrosine ligase-like protein, conserv
— OG7
TvY486_1101590 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
TvY486_1005840 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_0400920 ⚠
peroxisome biogenesis factor 1, putative
— OG7
TvY486_0503380 ⚠
peroxisome assembly protein, putative
— OG7
TvY486_0603270 ⚠
AAA ATPase, (fragment), valosin-containing pr
— OG7
TvY486_0702940 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_1109870 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_1008420 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_0503360 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.