TvY486_0502330

phosphoribosylpyrophosphate synthetase, putative
Trypanosoma vivax Y486 OG6: OG6_143547 OG7: OG7_0002319 175 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 175 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0806620 ⚠
acetyl-CoA carboxylase (fragment)
— +5 more Both
TvY486_0502575 ⚠
ribose-phosphate pyrophosphokinase, putative,
— +4 more Both
TvY486_0804650 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TvY486_1009350 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TvY486_1103090 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
TvY486_0404370 ⚠
RNA polymerase IIA largest subunit, (fragment
— Both
TvY486_0806890 ⚠
RNA polymerase IIA largest subunit, (fragment
— Both
TvY486_1002800 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
TvY486_1107670 ⚠
neurobeachin/beige protein, putative
— OG7
TvY486_0701710 ⚠
hypothetical protein, conserved
— OG7
TvY486_0700230 ⚠
FYVE zinc finger, putative
— OG7
TvY486_1111590 ⚠
glycosyl hydrolase, putative
— OG7
TvY486_0601080 ⚠
hypothetical protein, conserved
— OG7
TvY486_1008260 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0043390 ⚠
protein kinase, putative
— OG7
TvY486_1008310 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TvY486_0703750 ⚠
hypothetical protein, conserved
— OG7
TvY486_0807380 ⚠
hypothetical protein, conserved
— OG7
TvY486_1100480 ⚠
RNA polymerase I second largest subunit, puta
— OG7
TvY486_1101350 ⚠
Right handed beta helix region/Periplasmic co
— OG7
TvY486_0807740 ⚠
Cullin 6, putative
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1115360 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TvY486_1116920 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_0031930 ⚠
hypothetical protein
— OG7
TvY486_1114830 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0700445 ⚠
zinc finger protein, putative
— OG7
TvY486_0804780 ⚠
cullin, putative, (fragment)
— OG7
TvY486_0906610 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0706700 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TvY486_0704260 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TvY486_1116430 ⚠
histone deacetylase 2, putative
— OG7
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TvY486_0100900 ⚠
phosphatidylinositol 3-kinase, putative, (fra
— OG7
TvY486_0200840 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0803030 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
TvY486_1104500 ⚠
ATP-dependent RNA helicase, putative
— OG7
TvY486_0502265 ⚠
histone deacetylase, putative (fragment)
— OG7
TvY486_0029580 ⚠
hypothetical protein
— OG7
TvY486_0100010 ⚠
DNA-directed RNA polymerase III, putative (fr
— OG7
TvY486_1014740 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
TvY486_0304910 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
TvY486_0705180 ⚠
SpoU rRNA Methylase family, putative
— OG7
TvY486_0402270 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TvY486_0700650 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1100210 ⚠
RNA-binding protein, putative (fragment)
— OG7
TvY486_0024850 ⚠
hypothetical protein, conserved in T. vivax
— OG7
TvY486_1006120 ⚠
neurobeachin/beige protein, putative, (fragme
— OG7
TvY486_0805490 ⚠
cullin, putative
— OG7
TvY486_0905570 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.