TvY486_0402580

Zeta toxin, putative
Trypanosoma vivax Y486 OG6: OG6_115193 OG7: OG7_0017220 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_0032470 ⚠
hypothetical protein, conserved in T. vivax
— OG6
TvY486_0805800 ⚠
tubulin folding cofactor D, putative, (fragme
— Both
TvY486_0601460
hypothetical protein, conserved
— Both
TvY486_1113650 ⚠
ubiquitin ligase, putative (fragment)
— Both
TvY486_0801550
mannose-1-phosphate guanyltransferase, putati
— Both
TvY486_0014470 ⚠
ubiquitin ligase, putative, (fragment)
— Both
TvY486_0503220
ubiquitin-activating enzyme E1, putative, (fr
— Both
TY486_1009410
leucine-rich repeat protein (LRRP), putative
— Both
TvY486_1003780
vacuolar ATP synthase subunit D, putative, (f
— Both
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TvY486_1102510 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— Both
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— Both
TvY486_0804120 ⚠
hypothetical protein, conserved
— Both
TvY486_0900810 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0100300 ⚠
developmentally regulated phosphoprotein, put
— Both
TvY486_1013850
Histone chaperone Rttp106-like, putative
— Both
TvY486_0011310 ⚠
ribonuclease, putative, (fragment)
— Both
TvY486_0802360 ⚠
ribonuclease, putative, (fragment)
— Both
TvY486_1008230 ⚠
ribonuclease, putative
— Both
TvY486_0805930
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TvY486_1101900 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_1111570 ⚠
Adaptor protein complex AP-3 subunit beta-3 (
— OG7
TvY486_1009100 ⚠
beta adaptin, putative
— OG7
TvY486_1102710 ⚠
heat shock protein, putative
— OG7
TvY486_0302990 ⚠
heat shock protein 90, putative
— OG7
TvY486_0400570 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0020590 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0033450 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_0906670 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_0901510
DNA-damage inducible protein DDI1-like protei
— Both
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0904770 ⚠
synaptojanin (N-terminal domain), putative, (
— OG7
TvY486_1105670 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TvY486_0027600 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
TvY486_0029570 ⚠
hypothetical protein, conserved
— OG7
TvY486_0401600 ⚠
hypothetical protein, conserved
— OG7
TvY486_1005550 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TvY486_1004540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TvY486_0302010 ⚠
6-phosphofructo-2-kinase 1
— OG7
TvY486_0800510 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TvY486_0500690
threonyl-tRNA synthetase, putative
— Both
TvY486_0601190
kinesin, putative
— OG6
TvY486_0503710
dihydrolipoamide branched chain transacylase,
— Both
TvY486_0028470 ⚠
hypothetical protein, conserved in T. vivax,
— OG6
TvY486_0803220 ⚠
hypothetical protein, conserved
— Both
TvY486_1000090 ⚠
ATP synthase F1 subunit gamma
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.