TvY486_0801550

mannose-1-phosphate guanyltransferase, putative

Trypanosoma vivax Y486 OG6: OG6_100460 OG7: OG7_0001668 200 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 200 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_0705050 glutamine synthetase, putative	—	OG6 Tb927.7.4970 ↔ Tb927.8.2050 OG6 TCSYLVIO_001811 ↔ TCSYLVIO_007603 OG7 Tb927.7.4970 ↔ Tb927.8.2050 OG7 TCSYLVIO_001811 ↔ TCSYLVIO_007603	Both
TvY486_0302140 ⚠ inorganic pyrophosphatase, putative	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
TvY486_1107360 ⚠ acidocalcisomal pyrophosphatase, putative, (f	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
TvY486_1107390 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
TvY486_1107380 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 Tb927.11.7080 ↔ Tb927.8.2050 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007603 OG7 Tb927.11.7080 ↔ Tb927.8.2050 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007603	Both
TvY486_1007450 myo-inositol-1-phosphate synthase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
TvY486_1102510 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007603	OG7
TvY486_0706770 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007603	Both
TvY486_0403170 hypothetical protein, conserved	—	OG6 TCSYLVIO_003958 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003958 ↔ TCSYLVIO_007603	Both
TvY486_0032470 ⚠ hypothetical protein, conserved in T. vivax	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007603	OG6
TvY486_0805800 ⚠ tubulin folding cofactor D, putative, (fragme	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007603	Both
TvY486_0601460 hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007603	Both
TvY486_1113650 ⚠ ubiquitin ligase, putative (fragment)	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_007603	Both
TvY486_0305030 Metallopeptidase family M24/FACT complex subu	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010728	Both
TvY486_1010600 ⚠ heat shock protein 83, putative, (fragment)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0502160 ⚠ mitochondrial DNA polymerase beta, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010588 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010588	Both
TvY486_0301870 hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010323	Both
TvY486_0706370 ⚠ tRNA-dihydrouridine synthase 3, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009102	Both
TvY486_0502690 WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010560	Both
TvY486_0706570 ⚠ trans-sialidase, putative, (fragment)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009462 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009462	Both
TvY486_0703520 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010624	Both
TvY486_1001500 ⚠ methionyl-tRNA synthetase, putative, (fragmen	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
TvY486_0023660 ⚠ lipophosphoglycan biosynthetic protein, putat	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0101370 tRNA (Uracil-5-)-methyltransferase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008409	Both
TvY486_0038450 ⚠ trans-sialidase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009462 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009462	Both
TvY486_0039990 ⚠ trans-sialidase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009462 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009462	Both
TvY486_0503710 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009880	Both
TvY486_0303270 ⚠ heat shock protein, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0503220 ubiquitin-activating enzyme E1, putative, (fr	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010542	Both
TvY486_1111570 ⚠ Adaptor protein complex AP-3 subunit beta-3 (	—	OG7 TCSYLVIO_004597 ↔ TCSYLVIO_007603	OG7
TvY486_1009060 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007603	Both
TvY486_1003780 vacuolar ATP synthase subunit D, putative, (f	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_007603	Both
TY486_1009410 leucine-rich repeat protein (LRRP), putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007603	Both
TvY486_1010610 ⚠ heat shock protein 83	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0035480 ⚠ heat shock protein 85, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_1004520 PUB domain containing protein, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009932 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009932	Both
TvY486_0001070 ⚠ methionyl-tRNA synthetase, putative (fragment	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
TvY486_1010590 ⚠ heat shock protein 83, (fragment)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008621 +2 more	Both
TvY486_0023570 ⚠ ATP synthase F1 subunit gamma protein, putati	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009375	Both
TvY486_0801700 pteridine reductase 1	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008848	Both
TvY486_0017960 ⚠ trans-sialidase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009462 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009462	Both
TvY486_0022230 ⚠ hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
TvY486_0024490 ⚠ trans-sialidase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009462 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009462	Both
TvY486_1000090 ⚠ ATP synthase F1 subunit gamma	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_009375 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_009375	Both
TvY486_0704350 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010327	Both
TvY486_0014470 ⚠ ubiquitin ligase, putative, (fragment)	—	OG6 TCSYLVIO_006542 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_006542 ↔ TCSYLVIO_007603	Both
TvY486_0028470 ⚠ hypothetical protein, conserved in T. vivax,	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008446	OG6
TvY486_0803110 exonuclease, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_010944	Both
TvY486_0000680 ⚠ methionyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
TvY486_0803220 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_008446 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_008446	Both

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