TvY486_1015010

glycosomal malate dehydrogenase, putative
Trypanosoma vivax Y486 OG6: OG6_132322 OG7: OG7_0002342 129 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 129 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1103120 ⚠
ribosome assembly protein RRB1, putative
— OG7
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_0008090 ⚠
ATP synthase, putative (fragment)
— OG7
TvY486_1009320 ⚠
branch point binding protein, putative
— OG7
TvY486_0401650 ⚠
hypothetical protein, conserved
— OG7
TvY486_1004540 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TvY486_1111650 ⚠
vacuolar sorting-associated protein-like, put
— OG7
TvY486_1116740 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0906210 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
TvY486_0305030 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
TvY486_0701430 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TvY486_1012470 ⚠
hypothetical protein, conserved
— OG7
TvY486_1013190 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
TvY486_1006265 ⚠
Ribosomal protein S5, C-terminal domain conta
— OG7
TvY486_0706750 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TvY486_0100640 ⚠
conserved protein, unknown function
— OG7
TvY486_1002280 ⚠
Ubiquitin family, putative
— OG7
TvY486_0402160 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TvY486_0601330 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TvY486_0706920 ⚠
RNA-binding protein, putative
— OG7
TvY486_0702420 ⚠
guide RNA associated protein, GAP2
— OG7
TvY486_0702440 ⚠
guide RNA associated protein, GAP2
— OG7
TvY486_0800440 ⚠
hypothetical protein, conserved
— OG7
TvY486_1106970 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1013040 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TvY486_0037820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0037830 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_1106030 ⚠
hypothetical protein, conserved
— OG7
TvY486_1007580 ⚠
protein transport protein Sec23A, putative
— OG7
TvY486_0901510 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TvY486_0501270 ⚠
RNA pseudouridylate synthase, putative
— OG7
TvY486_0700560 ⚠
RNA pseudouridylate synthase, putative
— OG7
TvY486_0902760 ⚠
RNA pseudouridylate synthase-like protein, pu
— OG7
TvY486_1009570 ⚠
ubiquitin-protein ligase, putative
— OG7
TvY486_0404030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0807150 ⚠
hypothetical protein, conserved
— OG7
TvY486_0100790 ⚠
cyclophilin 15, putative
— OG7
TvY486_0805800 ⚠
tubulin folding cofactor D, putative, (fragme
— OG7
TvY486_0700420 ⚠
hypothetical protein, conserved
— OG7
TvY486_1112720 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TvY486_0400800 ⚠
V-type ATPase, A subunit, putative
— OG7
TvY486_0400810 ⚠
V-type ATPase, A subunit, putative, (fragment
— OG7
TvY486_0603950 ⚠
hypothetical protein, conserved
— OG7
TvY486_0101320 ⚠
amidohydrolase, putative
— OG7
TvY486_0101330 ⚠
amidohydrolase, putative
— OG7
TvY486_0021890 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0906650 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_1116410 ⚠
hypothetical protein, conserved
— OG7
TvY486_0604090 ⚠
calmodulin, putative
— OG7
TvY486_1008890 ⚠
pseudouridine synthase TruD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.