TvY486_0100640

conserved protein, unknown function
Trypanosoma vivax Y486 OG6: OG6_173713 OG7: OG7_0063852 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0700400
Cupin-like domain containing protein, putativ
— Both
TvY486_0029580 ⚠
hypothetical protein
— OG7
TvY486_0701280 ⚠
pseudouridylate synthase I, putative, (fragme
— OG7
TvY486_1114840 ⚠
Outer row dynein-assembly protein 7
— OG7
TvY486_0502980 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TvY486_0010920 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1015010 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TvY486_0800950 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
TvY486_1002100 ⚠
elongation factor 1-alpha, putative
— OG7
TvY486_1116130
phosphatidylinositol kinase, putative, (fragm
— OG7
TvY486_0024850 ⚠
hypothetical protein, conserved in T. vivax
— OG7
TvY486_1002090 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TvY486_0700445 ⚠
zinc finger protein, putative
— OG7
TvY486_0703750 ⚠
hypothetical protein, conserved
— OG7
TvY486_0700230 ⚠
FYVE zinc finger, putative
— OG7
TvY486_0701710 ⚠
hypothetical protein, conserved
— OG7
TvY486_0905580 ⚠
predicted zinc finger protein, zinc finger pr
— OG7
TvY486_0902820 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TvY486_1108060 ⚠
rrp44p homologue, putative
— OG7
TvY486_0602450 ⚠
pseudouridine synthase A-like protein, putati
— Both
TvY486_0101320 ⚠
amidohydrolase, putative
— Both
TvY486_0700500 ⚠
hypothetical protein, conserved
— Both
TvY486_0602010 ⚠
hypothetical protein, conserved
— OG7
TvY486_0402970 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TvY486_1004930 ⚠
dihydrouridine synthase domain protein, putat
— OG7
TvY486_0603580 ⚠
GTPase activator-like protein, putative
— OG7
TvY486_0404250 ⚠
dihydrouridine synthase, putative
— OG7
TvY486_0902760 ⚠
RNA pseudouridylate synthase-like protein, pu
— OG7
TvY486_0700560 ⚠
RNA pseudouridylate synthase, putative
— OG7
TvY486_1007580
protein transport protein Sec23A, putative
— OG7
TvY486_1008260 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0804880 ⚠
WW domain containing protein, putative
— OG7
TvY486_1006600 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
TvY486_0706920
RNA-binding protein, putative
— OG7
TvY486_1002740 ⚠
pseudouridylate synthase I, putative, (fragme
— OG7
TvY486_0006340 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TvY486_1106510 ⚠
eukaryotic release factor 3, putative
— OG7
TvY486_1002080 ⚠
elongation factor 1-alpha, putative
— OG7
TvY486_0803260 ⚠
DEAD/DEAH box helicase, putative
— OG7
TvY486_1014010 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TvY486_0906020 ⚠
ATP-dependent RNA helicase, putative
— OG7
TvY486_0702310
GTPase activating protein, putative, (fragmen
— Both
TvY486_0303400
XPC-binding domain/UBA/TS-N domain containing
— Both
TvY486_0600210
alanyl-tRNA synthetase, putative
— Both
TvY486_1013110 ⚠
Zn-finger in Ran binding protein and others/F
— Both
TvY486_1013040
PA26 p53-induced protein (sestrin), putative
— Both
TvY486_0501270 ⚠
RNA pseudouridylate synthase, putative
— Both
TvY486_1013030
hypothetical protein, conserved
— Both
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.