TvY486_0906650

ubiquitin-protein ligase, putative, (fragment)
Trypanosoma vivax Y486 OG6: OG6_146796 OG7: OG7_0002947 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0702420 ⚠
guide RNA associated protein, GAP2
— OG7
TvY486_0601860 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0400030 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1008260 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0801040 ⚠
ubiquitin-protein ligase, putative, (fragemnt
— OG7
TvY486_1110130 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0905840 ⚠
replication factor C, subunit 3, putative
— OG7
TvY486_1110160 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0603360 ⚠
replication factor C, subunit 2, putative
— OG7
TvY486_0100870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TvY486_1012470 ⚠
hypothetical protein, conserved
— OG7
TvY486_0601670 ⚠
co-chaperone, putative
— OG7
TvY486_1111150 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_1010490 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_0700310 ⚠
GTP-binding protein, putative
— OG7
TvY486_0903790 ⚠
GTP-binding protein, putative
— OG7
TvY486_0042910 ⚠
GTP-binding protein, putative
— OG7
TvY486_1102700 ⚠
GTPase protein, putative
— OG7
TvY486_1115100 ⚠
small nuclear ribonucleoprotein Sm-G
— OG7
TvY486_0503220 ⚠
ubiquitin-activating enzyme E1, putative, (fr
— OG7
TvY486_0503440 ⚠
u6 snrna-associated sm-like protein
— OG7
TvY486_0602190 ⚠
small nuclear ribonucleoprotein Sm-E
— OG7
TvY486_1111190 ⚠
regulator of chromosome condensation 1-like p
— OG7
TvY486_0901110 ⚠
u6 snrna-associated sm-like protein, Sm- like
— OG7
TvY486_1107120 ⚠
regulator of chromatin condensation, putative
— OG7
TvY486_0904540 ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
TvY486_0041460 ⚠
chromatin binding protein, putative
— OG7
TvY486_0706230 ⚠
BTB/POZ domain/Regulator of chromosome conden
— OG7
TvY486_0806820 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TvY486_0701030 ⚠
regulator of chromosome condensation, putativ
— OG7
TvY486_0701050 ⚠
hypothetical protein, conserved
— OG7
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0025980 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_0503300 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TvY486_0902180 ⚠
glutamate dehydrogenase, putative
— OG7
TvY486_0706920 ⚠
RNA-binding protein, putative
— OG7
TvY486_0703360 ⚠
p22 protein precursor, putative
— OG7
TvY486_1010650 ⚠
DNA mismatch repair protein MSH2, putative (f
— OG7
TvY486_1116410 ⚠
hypothetical protein, conserved
— OG7
TvY486_0905890 ⚠
hypothetical protein, conserved
— OG7
TvY486_0604090 ⚠
calmodulin, putative
— OG7
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— OG7
TvY486_1015010 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TvY486_0701280 ⚠
pseudouridylate synthase I, putative, (fragme
— OG7
TvY486_1002740 ⚠
pseudouridylate synthase I, putative, (fragme
— OG7
TvY486_0602450 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TvY486_1114120 ⚠
hypothetical protein, conserved
— OG7
TvY486_0302660 ⚠
protein kinase, putative
— OG7
TvY486_0700420 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.