TvY486_0601320

Eukaryotic translation initiation factor 4E-4
Trypanosoma vivax Y486 OG6: OG6_106272 OG7: OG7_0002303 176 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 176 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1110550 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TvY486_1115000 ⚠
Alpha/beta hydrolase family, putative
— OG7
TvY486_0038700 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_0403510 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_1112680 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TvY486_0005960 ⚠
hypothetical protein, conserved
— OG7
TvY486_0303220 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TvY486_0702090 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TvY486_0200400 ⚠
Vps51/Vps67, putative
— OG7
TvY486_1116420 ⚠
hypothetical protein, conserved
— OG7
TvY486_0300390 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TvY486_0302140 ⚠
inorganic pyrophosphatase, putative
— OG7
TvY486_0600970 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TvY486_0805130 ⚠
transaldolase, putative
— OG7
TvY486_1107360 ⚠
acidocalcisomal pyrophosphatase, putative, (f
— OG7
TvY486_1107390 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TvY486_1107380 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TvY486_1109230 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TvY486_1107910 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0005970 ⚠
5'-3' exonuclease, putative
— OG7
TvY486_0704970 ⚠
5'-3' exoribonuclease A, putative
— OG7
TvY486_1006180 ⚠
5'-3' exoribonuclease D, putative
— OG7
TvY486_0601580 ⚠
pdz domain containing protein, putative
— OG7
TvY486_1009730 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TvY486_0701820 ⚠
GMP synthase [glutamine-hydrolysing], (fragme
— OG7
TvY486_0305050 ⚠
nuclear transcription factor, putative
— OG7
TvY486_1109390 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TvY486_0900800 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TvY486_1007580 ⚠
protein transport protein Sec23A, putative
— OG7
TvY486_0804660 ⚠
hypothetical protein, conserved
— OG7
TvY486_1011250 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TvY486_0805420 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TvY486_0800270 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0010920 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1114840 ⚠
Outer row dynein-assembly protein 7
— OG7
TvY486_1007260 ⚠
ATP-dependent DEAD/H RNA helicae, putative
— OG7
TvY486_0501330 ⚠
ecotin, putative
— OG7
TvY486_0501230 ⚠
Ecotin-like protein
— OG7
TvY486_1005030 ⚠
ubiquitin-like protein, putative
— OG7
TvY486_1101230 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TvY486_1002630 ⚠
CS domain containing protein, putative
— OG7
TvY486_1100750 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
TvY486_1116490 ⚠
poly(A) polymerase, putative
— OG7
TvY486_1003700 ⚠
aspartate aminotransferase, putative
— OG7
TvY486_0304700 ⚠
UBX domain-containing protein
— OG7
TvY486_1000070 ⚠
Kinetoplast poly(A) polymerase 2
— OG7
TvY486_0301440 ⚠
hypothetical protein, conserved
— OG7
TvY486_1003680 ⚠
aspartate aminotransferase, putative, (fragme
— OG7
TvY486_0301960 ⚠
hypothetical protein, conserved (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.