TvY486_0706520

ATPase family associated with various cellular activities (AAA), putative
Trypanosoma vivax Y486 OG6: OG6_142131 OG7: OG7_0001167 113 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 113 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1104320 ⚠
hypothetical protein, conserved
— OG7
TvY486_0100870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TvY486_0009670 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1010650 ⚠
DNA mismatch repair protein MSH2, putative (f
— OG7
TvY486_0700160 ⚠
protein farnesyltransferase, putative
— OG7
TvY486_0500220 ⚠
hypothetical protein, conserved
— OG7
TvY486_0904540 ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
TvY486_1112790 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TvY486_0302660 ⚠
protein kinase, putative
— OG7
TvY486_0906650 ⚠
ubiquitin-protein ligase, putative, (fragment
— OG7
TvY486_0021890 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0700500 ⚠
hypothetical protein, conserved
— OG7
TvY486_0905890 ⚠
hypothetical protein, conserved
— OG7
TvY486_0907170 ⚠
hypothetical protein, conserved
— OG7
TvY486_0303280 ⚠
hypothetical protein, conserved
— OG7
TvY486_1112780 ⚠
hypothetical protein, conserved
— OG7
TvY486_0700420 ⚠
hypothetical protein, conserved
— OG7
TvY486_1012470 ⚠
hypothetical protein, conserved
— OG7
TvY486_0402400 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TvY486_0028120 ⚠
protein kinase
— OG7
TvY486_1107560 ⚠
protein kinase, putative, (fragment)
— OG7
TvY486_0503220 ⚠
ubiquitin-activating enzyme E1, putative, (fr
— OG7
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0400380 ⚠
hypothetical protein, conserved
— OG7
TvY486_0025980 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_1112680 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TvY486_0101620 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TvY486_0005960 ⚠
hypothetical protein, conserved
— OG7
TvY486_0800270 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_1014730 ⚠
hypothetical protein, conserved (fragment)
— OG7
TvY486_0802320 ⚠
5'-3' exoribonuclease C, putative
— OG7
TvY486_1114120 ⚠
hypothetical protein, conserved
— OG7
TvY486_1106720 ⚠
MRB1-associated protein
— OG7
TvY486_0600460 ⚠
cysteinyl-tRNA synthetase, putative, (fragmen
— OG7
TvY486_0705600 ⚠
TLD, putative
— OG7
TvY486_0502690 ⚠
WD domain, G-beta repeat, putative
— OG7
TvY486_1102350 ⚠
phenylalanyl-tRNA synthetase, putative, (frag
— OG7
TvY486_0501230 ⚠
Ecotin-like protein
— OG7
TvY486_0501330 ⚠
ecotin, putative
— OG7
TvY486_1007260 ⚠
ATP-dependent DEAD/H RNA helicae, putative
— OG7
TvY486_0301890 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TvY486_0901270 ⚠
kinetoplastid kinetochore protein 18
— OG7
TvY486_0702420 ⚠
guide RNA associated protein, GAP2
— OG7
TvY486_0305050 ⚠
nuclear transcription factor, putative
— OG7
TvY486_1001290 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TvY486_0702440 ⚠
guide RNA associated protein, GAP2
— OG7
TvY486_0701770 ⚠
R3H domain containing protein, putative
— OG7
TvY486_1114510 ⚠
hypothetical protein, conserved
— OG7
TvY486_0502190 ⚠
Beta-lactamase superfamily domain containing
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.