TvY486_0302220

eukaryotic translation initiation factor 2 subunit alpha
Trypanosoma vivax Y486 OG6: OG6_101220 OG7: OG7_0006220 37 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 37 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1103520
hypothetical protein, conserved (fragment)
— Both
TvY486_1113190 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TvY486_0900770
hypothetical protein, conserved (fragment)
— Both
TvY486_1109010 ⚠
hypothetical protein, conserved
— Both
TvY486_0905050 ⚠
protein kinase A catalytic subunit, putative
— OG6
TvY486_1012660 ⚠
protein kinase A catalytic subunit 3
— OG6
TvY486_0602190 ⚠
small nuclear ribonucleoprotein Sm-E
— Both
TvY486_0502520
translation initiation factor, putative
— Both
TvY486_1114110
eukaryotic translation initiation factor, put
— Both
TvY486_0801910
5'-AMP-activated protein kinase subunit beta,
— Both
TvY486_0702440 ⚠
guide RNA associated protein, GAP2
— Both
TvY486_0300390 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TvY486_0501010 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TvY486_0902660 ⚠
methyltransferase domain containing protein,
— OG7
TvY486_1115100 ⚠
small nuclear ribonucleoprotein Sm-G
— OG7
TvY486_0503060
hypothetical protein, conserved
— OG7
TvY486_0503440 ⚠
u6 snrna-associated sm-like protein
— OG7
TvY486_0901110 ⚠
u6 snrna-associated sm-like protein, Sm- like
— OG7
TvY486_0904540 ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
TvY486_0011520 ⚠
14-3-3 protein-like protein, putative
— Both
TvY486_0900800
deoxyhypusine hydroxylase, putative
— Both
TvY486_0100590
serine/threonine protein phosphatase, (fragme
— Both
TvY486_1113530 ⚠
cyclin 1
— Both
TvY486_1110110 ⚠
14-3-3 protein 1, putative
— Both
TvY486_0045820 ⚠
hypothetical protein (fragment)
— Both
TvY486_1113540 ⚠
cyclin 1
— Both
TvY486_1012540
prolyl-tRNA synthetase, putative
— Both
TvY486_1110590 ⚠
Domain of unknown function (DUF3846)/TPR repe
— Both
TvY486_0706610 ⚠
methyltransferase domain containing protein,
— Both
TvY486_1107200 ⚠
14-3-3 protein 2, putative
— Both
TvY486_0004050 ⚠
hypothetical protein
— Both
TvY486_0600970 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TvY486_0601850
adenosine kinase, putative
— Both
TvY486_0604030
UV excision repair RAD23 protein, putative, (
— Both
TvY486_1010860
hypothetical protein, conserved (fragment)
— Both
TvY486_0200900
guide RNA associated protein 1, putative
— Both
TvY486_0702420 ⚠
guide RNA associated protein, GAP2
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.