TvY486_0503270 – TrypsnetDB2

TvY486_0503270

dihydroorotate dehydrogenase, putative, (fragment)

Trypanosoma vivax Y486 OG6: OG6_100674 OG7: OG7_0005744 16 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 16 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_0401760 ⚠ NADPH-dependent FMN/FAD containing oxidoreduc	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_003840 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	Both
TvY486_1105240 ⚠ aspartate aminotransferase, mitochondrial, pu	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005115 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005115	Both
TvY486_0302750 hypothetical protein, conserved	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_004409 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_004409	Both
TvY486_0012100 nitrilase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005176 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005176	Both
TvY486_0000930 ⚠ cysteine peptidase C (CPC), putative, (fragme	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_001905	OG6
TvY486_0800150 ⚠ peptidyl-prolyl cis-trans isomerase/rotamase,	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG6
TvY486_0703740 ⚠ poly(A) polymerase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_010610 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_010610	Both
TvY486_1003700 ⚠ aspartate aminotransferase, putative	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005115 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005115	Both
TvY486_0029220 hypothetical protein (fragment)	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_008914 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_008914	Both
TvY486_1003680 ⚠ aspartate aminotransferase, putative, (fragme	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_005115 OG7 TCSYLVIO_001184 ↔ TCSYLVIO_005115	Both
TvY486_0600060 ⚠ cysteine peptidase C (CPC), CPC cysteine pept	—	OG6 TCSYLVIO_001184 ↔ TCSYLVIO_001905	OG6
TvY486_0302300 inosine-adenosine-guanosine-nucleoside hydrol	—	OG6 Tb927.3.2960 ↔ Tb927.5.3830 OG7 Tb927.3.2960 ↔ Tb927.5.3830	Both
TvY486_0602230 pyridoxal kinase, putative	—	OG6 Tb927.5.3830 ↔ Tb927.6.2740 OG7 Tb927.5.3830 ↔ Tb927.6.2740	Both
TvY486_1109190 ⚠ p450 reductase, putative	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG7
TvY486_0302520 ⚠ poly(A) polymerase, putative	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_010610	OG7
TvY486_0906550 ⚠ cytochrome P450 reductase, putative	—	OG7 TCSYLVIO_001184 ↔ TCSYLVIO_003840	OG7

Orthogroup expansion — connections between the query proteins

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