TvY486_0602230

pyridoxal kinase, putative
Trypanosoma vivax Y486 OG6: OG6_102185 OG7: OG7_0006572 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1108080
cystathionine beta-synthase, putative
— Both
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TvY486_0301540 ⚠
translation elongation factor EF-2, putative
— OG7
TvY486_0200780 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_1108110 ⚠
D-alanyl-glycyl endopeptidase, putative
— OG7
TvY486_0200790 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_1014790 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TvY486_1002570 ⚠
malate dehydrogenase, putative
— OG7
TvY486_0503270
dihydroorotate dehydrogenase, putative, (frag
— Both
TvY486_1007790
2,3-bisphosphoglycerate-independent phosphogl
— Both
TvY486_0903050
spermidine synthase, putative
— Both
TvY486_1113660
ribonucleoside-diphosphate reductase small ch
— Both
TvY486_1002580 ⚠
malate dehydrogenase, putative
— Both
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— Both
TvY486_1004580 ⚠
elongation factor 2, putative, (fragment)
— Both
TvY486_1112250
cytosolic malate dehydrogenase, putative
— Both
TvY486_0302300
inosine-adenosine-guanosine-nucleoside hydrol
— Both
TvY486_0201160 ⚠
trypanothione synthetase (fragment)
— Both
TvY486_0805670
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TvY486_0802010
3-ketoacyl-CoA thiolase, putative, (fragment)
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.