TvY486_0805670

3-hydroxy-3-methylglutaryl-CoA synthase, putative
Trypanosoma vivax Y486 OG6: OG6_101064 OG7: OG7_0006553 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0902120 ⚠
tryparedoxin peroxidase, putative, (fragment)
— Both
TvY486_1004030 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
TvY486_1108170 ⚠
DEAD box RNA helicase, putative, RNA helicase
— OG7
TvY486_0603330 ⚠
leucyl/phenylalanyl-tRNA protein transferase,
— OG7
TvY486_0100510
cytidine triphosphate synthase, putative, (fr
— Both
TvY486_0303770
Fumarate hydratase class I, cytosolic
— Both
TvY486_0902100 ⚠
tryparedoxin peroxidase, putative
— Both
TvY486_0902140 ⚠
tryparedoxin peroxidase, putative, (fragment)
— Both
TvY486_0005250 ⚠
tryparedoxin peroxidase, putative
— Both
TvY486_0901660 ⚠
eukaryotic initiation factor 4a, putative
— OG7
TvY486_0902150 ⚠
tryparedoxin peroxidase, putative
— Both
TvY486_0003245 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0801490 ⚠
tryparedoxin peroxidase, putative, peroxidoxi
— Both
TvY486_0802010
3-ketoacyl-CoA thiolase, putative, (fragment)
— Both
TvY486_0803650
hypothetical protein, conserved
— Both
TvY486_1116970
nucleoside diphosphate kinase, putative
— Both
TvY486_1108080
cystathionine beta-synthase, putative
— Both
TvY486_0806100 ⚠
protein kinase, putative
— Both
TvY486_1007930 ⚠
hypothetical protein, conserved
— OG7
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TvY486_0301540 ⚠
translation elongation factor EF-2, putative
— OG7
TvY486_1109730 ⚠
NOL1/NOP2/sun family, putative
— OG7
TvY486_0000500 ⚠
NOL1/NOP2/sun family protein, putative, (frag
— OG7
TvY486_0906500 ⚠
hypothetical protein, conserved
— OG7
TvY486_1004200 ⚠
hypothetical protein, conserved
— OG7
TvY486_1011130 ⚠
hypothetical protein, conserved
— OG7
TvY486_0303810 ⚠
NOL1/NOP2/sun family, putative
— OG7
TvY486_0021270 ⚠
protein kinase, putative
— Both
TvY486_0302770 ⚠
hypothetical protein, conserved
— OG7
TvY486_1102100 ⚠
choline/ethanolamine kinase, putative
— OG7
TvY486_0301460 ⚠
hypothetical protein, conserved
— OG7
TvY486_1116470 ⚠
NOL1/NOP2/sun family, putative
— OG7
TvY486_0403570 ⚠
nucleolar protein, putative
— OG7
TvY486_1107290 ⚠
serine/threonine protein kinase, putative
— OG7
TvY486_1107310 ⚠
protein kinase, putative
— OG7
TvY486_1103700 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
TvY486_1104540
hypothetical protein, conserved
— Both
TvY486_1013540
aconitase, putative, (fragment), aconitase, (
— Both
TvY486_1007240
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— Both
TvY486_1004580 ⚠
elongation factor 2, putative, (fragment)
— Both
TvY486_0800330
serine/threonine kinase, putative
— OG6
TvY486_1000480 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
TvY486_0503260
aspartate carbamoyltransferase, putative
— Both
TvY486_1001610 ⚠
hypothetical protein, conserved
— Both
TvY486_1111970
translation initiation factor 2 subunit, puta
— Both
TvY486_1002910 ⚠
enolase, putative
— Both
TvY486_1002920 ⚠
enolase, putative, (fragment)
— Both
TvY486_0705280
Putative Phosphatase/Protein of unknown funct
— OG6
TvY486_0301600
succinyl-CoA synthetase alpha subunit, putati
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.