TvY486_0301600

succinyl-CoA synthetase alpha subunit, putative
Trypanosoma vivax Y486 OG6: OG6_100834 OG7: OG7_0005210 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1007240
succinyl-CoA ligase [GDP-forming] beta-chain,
— +2 more Both
TvY486_0303220 ⚠
carnitine/choline acetyltransferase, putative
— Both
TvY486_1003700 ⚠
aspartate aminotransferase, putative
— Both
TvY486_1101500 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
TvY486_0805600 ⚠
glycine acetyltransferase, putative, 2-amino-
— Both
TvY486_0601230
phosphatase 2C, putative
— OG6
TvY486_0902335 ⚠
arginine kinase, putative, (fragment)
— Both
TvY486_1112540
hd phosphohydrolase family protein
— Both
TvY486_1111100
ATP-dependent protease subunit HslV, putative
— Both
TvY486_0402570
pyroglutamyl-peptidase I, putative
— Both
TvY486_0902320 ⚠
arginine kinase, putative
— Both
TvY486_0803180
Mitogen-activated protein kinase 10, putative
— OG6
TvY486_1109480
ribose 5-phosphate isomerase, putative
— Both
TvY486_1013710
N-myristoyl transferase, putative
— Both
TvY486_0705830
deoxyribose-phosphate aldolase, putative
— Both
TvY486_1002570 ⚠
malate dehydrogenase, putative
— OG7
TvY486_1014790 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TvY486_1107260 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
TvY486_1103960 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
TvY486_1101240 ⚠
reductase, putative
— OG7
TvY486_1116370 ⚠
cytochrome-b5 reductase, putative
— OG7
TvY486_0702090 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TvY486_0400740 ⚠
serine-palmitoyl-CoA transferase, putative, (
— OG7
TvY486_1004080 ⚠
serine palmitoyltransferase, putative
— OG7
TvY486_1107910 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0043010 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TvY486_0400060 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
TvY486_1117730
dihydrolipoyl dehydrogenase, putative
— Both
TvY486_1105620 ⚠
malic enzyme, putative
— Both
TvY486_1100750 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_0013260 ⚠
cytochrome-b5 reductase, putative (fragment)
— Both
TvY486_0701640 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TvY486_0702600 ⚠
NADH-cytochrome b5 reductase, putative
— Both
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_0802010
3-ketoacyl-CoA thiolase, putative, (fragment)
— Both
TvY486_0701650 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TvY486_0403110
uracil phosphoribosyltransferase, putative, (
— Both
TvY486_0805670
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TvY486_1009730
Protein of unknown function (DUF2870), putati
— Both
TvY486_1013590
pyruvate kinase 1, putative, (fragment)
— Both
TvY486_1003680 ⚠
aspartate aminotransferase, putative, (fragme
— Both
TvY486_0904260
peptidyl-prolyl cis-trans isomerase (cyclophi
— OG6
TvY486_0701820
GMP synthase [glutamine-hydrolysing], (fragme
— Both
TvY486_1117420
enoyl-CoA hydratase/isomerase family protein,
— Both
TvY486_1002580 ⚠
malate dehydrogenase, putative
— Both
TvY486_1001370 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— Both
TvY486_1001390 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— Both
TvY486_0805130
transaldolase, putative
— Both
TvY486_0805760
transketolase, putative
— Both
TvY486_1105700
triosephosphate isomerase, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.