TvY486_1002570

malate dehydrogenase, putative
Trypanosoma vivax Y486 OG6: OG6_158331 OG7: OG7_0004751 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0903050 ⚠
spermidine synthase, putative
— OG7
TvY486_1009680 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TvY486_0400940 ⚠
ruvB-like DNA helicase, putative
— OG7
TvY486_0801120 ⚠
protein phosphatase 2A, regulatory subunit B,
— OG7
TvY486_0503680 ⚠
prolyl oligopeptidase, putative, Serine pepti
— OG7
TvY486_1007890 ⚠
prolyl endopeptidase
— OG7
TvY486_0705020 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TvY486_1100690 ⚠
sodium/hydrogen exchanger, putative
— OG7
TvY486_1010290 ⚠
trypanothione reductase, putative
— OG7
TvY486_1113690 ⚠
oligopeptidase b
— OG7
TvY486_0501850 ⚠
sodium/hydrogen exchanger, putative
— OG7
TvY486_0101330 ⚠
amidohydrolase, putative
— OG7
TvY486_0101320 ⚠
amidohydrolase, putative
— OG7
TvY486_1014210 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
TvY486_0705830 ⚠
deoxyribose-phosphate aldolase, putative
— OG7
TvY486_1102580 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
TvY486_1000480 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
TvY486_1108170 ⚠
DEAD box RNA helicase, putative, RNA helicase
— OG7
TvY486_1004030 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
TvY486_0901660 ⚠
eukaryotic initiation factor 4a, putative
— OG7
TvY486_0600140 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TvY486_0807310 ⚠
diadenosine tetraphosphatase, putative
— OG7
TvY486_0807440 ⚠
diadenosine tetraphosphatase, putative
— OG7
TvY486_1007700 ⚠
hypothetical protein, conserved
— OG7
TvY486_0501330 ⚠
ecotin, putative
— OG7
TvY486_0501230 ⚠
Ecotin-like protein
— OG7
TvY486_0304740 ⚠
FHA domain containing protein, putative
— OG7
TvY486_0201160 ⚠
trypanothione synthetase (fragment)
— OG7
TvY486_0603560 ⚠
chaperonin HSP60/CNP60, putative
— OG7
TvY486_0200790 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_0602230 ⚠
pyridoxal kinase, putative
— OG7
TvY486_0013260 ⚠
cytochrome-b5 reductase, putative (fragment)
— OG7
TvY486_0701640 ⚠
Adenine phosphoribosyltransferase, putative
— OG7
TvY486_0302300 ⚠
inosine-adenosine-guanosine-nucleoside hydrol
— OG7
TvY486_1108110 ⚠
D-alanyl-glycyl endopeptidase, putative
— OG7
TvY486_1107260 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
TvY486_1103960 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
TvY486_1112250 ⚠
cytosolic malate dehydrogenase, putative
— OG7
TvY486_0702600 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
TvY486_1101240 ⚠
reductase, putative
— OG7
TvY486_0401800 ⚠
ruvB-like DNA helicase, putative
— OG7
TvY486_1006380 ⚠
chaperonin HSP60, mitochondrial precursor, pu
— OG7
TvY486_0905640 ⚠
replication factor A protein 3, putative
— OG7
TvY486_1007790 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
TvY486_1006480 ⚠
chaperonin HSP60, mitochondrial precursor, pu
— OG7
TvY486_1007240 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— OG7
TvY486_1116370 ⚠
cytochrome-b5 reductase, putative
— OG7
TvY486_1105700 ⚠
triosephosphate isomerase, putative
— OG7
TvY486_0701650 ⚠
Adenine phosphoribosyltransferase, putative
— OG7
TvY486_0200780 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.