TvY486_1108080

cystathionine beta-synthase, putative
Trypanosoma vivax Y486 OG6: OG6_100154 OG7: OG7_0002172 74 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 74 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0801980
acetyl-CoA synthetase, putative, (fragment)
— +1 more Both
TvY486_0800460
phosphoacetylglucosamine mutase, putative, (f
— +2 more Both
TvY486_0201160 ⚠
trypanothione synthetase (fragment)
— Both
TvY486_1007790
2,3-bisphosphoglycerate-independent phosphogl
— Both
TvY486_1104200 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
TvY486_1113810
Uncharacterised protein family (UPF0160), put
— OG6
TvY486_0100510
cytidine triphosphate synthase, putative, (fr
— Both
TvY486_0805670
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TvY486_0805600 ⚠
glycine acetyltransferase, putative, 2-amino-
— Both
TvY486_0802010
3-ketoacyl-CoA thiolase, putative, (fragment)
— Both
TvY486_1113660
ribonucleoside-diphosphate reductase small ch
— Both
TvY486_0201360
branched-chain amino acid aminotransferase, p
— Both
TvY486_0403570 ⚠
nucleolar protein, putative
— OG7
TvY486_0903050
spermidine synthase, putative
— Both
TvY486_1112250
cytosolic malate dehydrogenase, putative
— Both
TvY486_0302300
inosine-adenosine-guanosine-nucleoside hydrol
— Both
TvY486_0602230
pyridoxal kinase, putative
— Both
TvY486_0304120 ⚠
Aminopeptidase M1, putative (fragment)
— Both
TvY486_0201060 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TvY486_1112290 ⚠
heat shock protein 70, putative, (fragment)
— OG6
TvY486_1108110 ⚠
D-alanyl-glycyl endopeptidase, putative
— OG7
TvY486_1107000 ⚠
cytochrome b5, putative
— OG7
TvY486_1114490 ⚠
cytochrome b5, putative
— OG7
TvY486_0302860 ⚠
cytochrome b-domain protein, putative
— OG7
TvY486_0003610 ⚠
cytochrome b, putative
— OG7
TvY486_1009680
mitochondrial intermediate peptidase, putativ
— OG7
TvY486_1103700 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
TvY486_0200780 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_1004080 ⚠
serine palmitoyltransferase, putative
— OG7
TvY486_1117110 ⚠
cAMP response protein 1, putative
— OG7
TvY486_0400740 ⚠
serine-palmitoyl-CoA transferase, putative, (
— OG7
TvY486_0200790 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_0900730 ⚠
methyltransferase domain containing protein,
— OG7
TvY486_1109730 ⚠
NOL1/NOP2/sun family, putative
— OG7
TvY486_0000500 ⚠
NOL1/NOP2/sun family protein, putative, (frag
— OG7
TvY486_0303810 ⚠
NOL1/NOP2/sun family, putative
— OG7
TvY486_0402650 ⚠
Protein of unknown function (DUF3808), putati
— OG7
TvY486_0700470 ⚠
heat shock 70 kDa protein, putative
— OG6
TvY486_0902010 ⚠
DNA topoisomerase II, putative, (fragment)
— Both
TvY486_0601530 ⚠
nitrate reductase, putative
— Both
TvY486_0706050
mercaptopyruvate sulfurtransferase, putative
— Both
TvY486_1102800
UDP-galactose 4-epimerase, putative
— Both
TvY486_1011680 ⚠
tyrosine protein kinase, putative, protein ki
— OG6
TvY486_1015430 ⚠
mitogen-activated protein kinase, putative
— OG6
TvY486_0017320
tyrosine aminotransferase
— Both
TvY486_1110190
Trypanosoma vivax, S-adenosyl-L-homocysteine
— Both
TvY486_0904950
kinetoplastid kinetochore protein 3, putative
— Both
TvY486_0301430
Xaa-Pro aminopeptidase, putative
— Both
TvY486_0802120
5-methyltetrahydropteroyltriglutamate-homocys
— Both
TvY486_1008120
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.