TvY486_0201060

Mitochondrial-processing peptidase subunit alpha
Trypanosoma vivax Y486 OG6: OG6_102381 OG7: OG7_0001887 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0302860 ⚠
cytochrome b-domain protein, putative
— OG7
TvY486_1104400 ⚠
Uncharacterized ACR, COG1678, putative
— Both
TvY486_1105070 ⚠
hypothetical protein, conserved
— Both
TvY486_0806390 ⚠
WD domain, G-beta repeat, putative
— Both
TvY486_1101390 ⚠
hypothetical protein, conserved
— Both
TvY486_0304430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
TvY486_1104700 ⚠
protein kinase A regulatory subunit
— Both
TvY486_0900470 ⚠
kynureninase, putative
— Both
TvY486_0603290 ⚠
hypothetical protein, conserved
— Both
TvY486_1109420 ⚠
NADH dehydrogenase subunit NB6M, putative
— OG7
TvY486_0500660 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TvY486_0801280 ⚠
cytochrome c1, heme protein, mitochondrial, p
— OG7
TvY486_0400910 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TvY486_1012450 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TvY486_1012640 ⚠
hypothetical protein, conserved
— OG7
TvY486_0003610 ⚠
cytochrome b, putative
— OG7
TvY486_0801250 ⚠
pitrilysin-like metalloprotease, putative, me
— Both
TvY486_0706880 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TvY486_1114490 ⚠
cytochrome b5, putative
— OG7
TvY486_1107000 ⚠
cytochrome b5, putative
— OG7
TvY486_1117110 ⚠
cAMP response protein 1, putative
— OG7
TvY486_1012430 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TvY486_0906450 ⚠
ankyrin repeat protein, putative
— OG7
TvY486_0906740 ⚠
ribonuclease, putative
— OG7
TvY486_0903710 ⚠
GTP-binding protein, putative
— OG7
TvY486_1009680 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TvY486_1109070 ⚠
ribonuclease II-like protein, putative, (frag
— OG7
TvY486_0902820 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TvY486_1115290 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TvY486_1114290 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TvY486_1105490 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TvY486_0706050 ⚠
mercaptopyruvate sulfurtransferase, putative
— Both
TvY486_0400310 ⚠
Alpha/beta hydrolase family, putative
— Both
TvY486_0603280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_0603230 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_0603220 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_1108080 ⚠
cystathionine beta-synthase, putative
— Both
TvY486_1008230 ⚠
ribonuclease, putative
— Both
TvY486_1006770 ⚠
developmentally regulated GTP-binding protein
— Both
TvY486_1110190 ⚠
Trypanosoma vivax, S-adenosyl-L-homocysteine
— Both
TvY486_0017320 ⚠
tyrosine aminotransferase
— Both
TvY486_1013290 ⚠
RNA-binding protein 29, putative
— Both
TvY486_0800460 ⚠
phosphoacetylglucosamine mutase, putative, (f
— Both
TvY486_1015430 ⚠
mitogen-activated protein kinase, putative
— OG6
TvY486_1011680 ⚠
tyrosine protein kinase, putative, protein ki
— OG6
TvY486_1107170 ⚠
hypothetical protein, conserved
— Both
TvY486_1102800 ⚠
UDP-galactose 4-epimerase, putative
— Both
TvY486_0901570 ⚠
mitochondrial-processing peptidase subunit be
— Both
TvY486_0601530 ⚠
nitrate reductase, putative
— Both
TvY486_1005760 ⚠
hypothetical protein, conserved (fragment)
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.