C4B63_150g37 – TrypsnetDB2

C4B63_150g37

short chain 3-hydroxyacyl-CoA dehydrogenase

Trypanosoma cruzi Dm28c 2018 OG6: OG6_101042 OG7: OG7_0000744 18 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 18 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
C4B63_9g516 ⚠ heat shock protein Hsp20	—	OG6 TCSYLVIO_004068 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_004068 ↔ TCSYLVIO_005016	Both
C4B63_7g430 ⚠ 1,2-Dihydroxy-3-keto-5-methylthiopentene diox	—	OG7 TCSYLVIO_005016 ↔ TCSYLVIO_005475	OG7
C4B63_145g3 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_77g74 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_77g46 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_145g18 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_145g28 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_82g121 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_82g107 ⚠ NADP-dependent alcohol hydrogenase	—	OG6 TCSYLVIO_000028 ↔ TCSYLVIO_005016 OG7 TCSYLVIO_000028 ↔ TCSYLVIO_005016	Both
C4B63_39g329 ⚠ glycyl-tRNA synthetase	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_009222 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_009222	Both
C4B63_4g136 ⚠ N-myristoyl transferase	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_006126 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_006126	Both
C4B63_160g33 ⚠ ubiquitin-activating enzyme E1	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_005839 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_005839	Both
C4B63_149g22 ⚠ agmatinase	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_006042	OG6
C4B63_2g786 ⚠ ubiquitin-activating enzyme E1	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_005839 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_005839	Both
C4B63_16g331 ⚠ ubiquitin-activating enzyme E1	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_005839 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_005839	Both
C4B63_19g43 ⚠ 1,2-Dihydroxy-3-keto-5-methylthiopentene diox	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_005475 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_005475	Both
C4B63_4g462 ⚠ arginase	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_006042 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_006042	Both
C4B63_4g137 ⚠ N-myristoyl transferase	—	OG6 TCSYLVIO_005016 ↔ TCSYLVIO_006126 OG7 TCSYLVIO_005016 ↔ TCSYLVIO_006126	Both

Orthogroup expansion — connections between the query proteins

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