C4B63_17g254

NAD+ synthase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100679 OG7: OG7_0004572 29 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 29 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_13g207
Mitogen-activated protein kinase 6
— OG6
C4B63_3g1101 ⚠
mitochondrial processing peptidase, beta subu
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g522 ⚠
choline kinase
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_7g135
Hydroxymethylglutaryl-CoA lyase, mitochondria
— Both
C4B63_51g112
conserved hypothetical protein
— Both
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— Both
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_2g388
conserved hypothetical protein
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_3g1118 ⚠
choline/ethanolamine kinase
— Both
C4B63_48g163
ARF-like 2 binding protein BART
— Both
C4B63_87g17 ⚠
pitrilysin-like metalloprotease
— Both
C4B63_3g1122 ⚠
choline/ethanolamine kinase
— Both
C4B63_147g45 ⚠
kynureninase
— Both
C4B63_11g10
KIF1-binding protein
— Both
C4B63_25g253
otubain cysteine peptidase, Clan CA, family C
— Both
C4B63_13g149
conserved hypothetical protein
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_6g444
phosphonopyruvate decarboxylase
— Both
C4B63_7g81
twinfilin
— Both
C4B63_30g187
deoxyuridine triphosphatase
— Both
C4B63_18g342
NUDIX hydrolase domain-like domain-containing
— Both
C4B63_85g69 ⚠
mitochondrial-processing peptidase subunit be
— Both
C4B63_210g32 ⚠
p-nitrophenylphosphatase
— Both
C4B63_210g33 ⚠
p-nitrophenylphosphatase
— Both
C4B63_200g30 ⚠
p-nitrophenylphosphatase
— Both
C4B63_24g246 ⚠
kynureninase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.