C4B63_26g207

mismatch repair protein MSH3
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105075 OG7: OG7_0001337 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_528g4 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_6g98 ⚠
RNA polymerase I
— OG7
C4B63_528g3 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_8g530 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_528g2 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_52g35 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_35g1396c ⚠
ubiquitin fold modifier protein
— Both
C4B63_28g129 ⚠
replication factor C, subunit 1
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_2g176 ⚠
elongation factor 1-alpha
— OG6
C4B63_84g82 ⚠
DNA mismatch repair protein MSH2
— Both
C4B63_57g111 ⚠
RNA editing 3' terminal uridylyl transferase
— Both
C4B63_43g155 ⚠
protein kinase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.