C4B63_2g721

DNA repair protein RAD2
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101242 OG7: OG7_0001893 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_20g361 ⚠
uracil phosphoribosyltransferase
— OG6
C4B63_300g18 ⚠
Glycerophosphoryl diester phosphodiesterase f
— OG6
C4B63_34g320 ⚠
Glycerophosphoryl diester phosphodiesterase f
— OG6
C4B63_28g25 ⚠
pyruvate dehydrogenase (lipoamide) kinase
— OG6
C4B63_12g234 ⚠
protein transport protein Sec31
— OG6
C4B63_7g383 ⚠
epsilon-adaptin
— OG6
C4B63_6g119 ⚠
oxidoreductase-like protein
— OG6
C4B63_293g30c ⚠
peptidyl-prolyl cis-trans isomerase
— OG6
C4B63_41g251 ⚠
arginine N-methyltransferase
— OG6
C4B63_4g120 ⚠
U2 small nuclear ribonucleoprotein 40K
— OG6
C4B63_23g186 ⚠
aspartyl aminopeptidase
— OG6
C4B63_157g28 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG6
C4B63_73g1 ⚠
arginine N-methyltransferase
— OG6
C4B63_127g50 ⚠
Protein PPP4R3C
— OG6
C4B63_49g325c ⚠
peptidyl-prolyl cis-trans isomerase
— OG6
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG6
C4B63_4g121 ⚠
U2 small nuclear ribonucleoprotein 40K
— OG6
C4B63_2g289 ⚠
Hypoxia up-regulated protein 1 (Fragment)
— OG6
C4B63_171g30 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG6
C4B63_4g368 ⚠
serine/threonine protein phosphatase type 5
— OG6
C4B63_86g54 ⚠
Hypoxia up-regulated protein 1 (Fragment)
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.