C4B63_43g125

centromere/microtubule binding protein cbf5
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100327 OG7: OG7_0003591 23 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 23 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g316 ⚠
ruvB-like DNA helicase
— +1 more Both
C4B63_7g212 ⚠
ruvB-like DNA helicase
— +3 more Both
C4B63_263g7 ⚠
ruvB-like DNA helicase
— +1 more Both
C4B63_2g566
phenylalanyl-tRNA synthetase
— Both
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_26g202
ribosomal protein S6
— OG7
C4B63_41g251 ⚠
arginine N-methyltransferase
— OG7
C4B63_60g173 ⚠
arginine N-methyltransferase, type I
— OG7
C4B63_73g1 ⚠
arginine N-methyltransferase
— OG7
C4B63_30g232 ⚠
protein arginine n-methyltransferase 7
— OG7
C4B63_7g236 ⚠
regulatory subunit of protein kinase a-like p
— Both
C4B63_7g417
snoRNP protein GAR1
— Both
C4B63_128g59
dihydrolipoamide branched chain transacylase
— Both
C4B63_13g978c
nucleolar RNA-binding protein
— Both
C4B63_23g39 ⚠
arginine N-methyltransferase
— Both
C4B63_2g5
casein kinase II
— OG6
C4B63_85g51 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_85g55 ⚠
fatty acyl CoA syntetase 1
— Both
C4B63_206g21 ⚠
fatty acyl CoA synthetase
— Both
C4B63_47g115 ⚠
fatty acyl CoA synthetase
— Both
C4B63_85g53 ⚠
fatty acyl CoA synthetase 2
— Both
C4B63_85g54 ⚠
fatty acyl CoA synthetase 2
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.