C4B63_59g124

MRB1 complex subunit MRB3010
Trypanosoma cruzi Dm28c 2018 OG6: OG6_117115 OG7: OG7_0033980 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_204g32 ⚠
mitochondrial RNA binding protein
— Both
C4B63_8g50
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_42g230
mitochondrial RNA binding protein 1
— Both
C4B63_8g530 ⚠
RNA editing 3' terminal uridylyl transferase
— Both
C4B63_76g32
guide RNA associated protein, GAP2
— Both
C4B63_72g115 ⚠
conserved hypothetical protein
— Both
C4B63_276g17 ⚠
conserved hypothetical protein
— Both
C4B63_42g170
conserved hypothetical protein
— Both
C4B63_13g43
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_9g524
eukaryotic translation initiation factor 3 su
— Both
C4B63_16g95
conserved hypothetical protein
— Both
C4B63_93g66
conserved hypothetical protein
— Both
C4B63_22g95
conserved hypothetical protein
— Both
C4B63_14g215
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_13g304 ⚠
mitochondrial RNA binding protein
— Both
C4B63_52g35 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_528g2 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_528g3 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_6g98 ⚠
RNA polymerase I
— OG7
C4B63_528g4 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_57g111 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
C4B63_85g62 ⚠
KREL1
— OG7
C4B63_2g798 ⚠
Putative pentatricopeptide repeat-containing
— OG7
C4B63_48g160 ⚠
mitochondrial RNA binding complex 1 subunit
— OG7
C4B63_21g31 ⚠
conserved hypothetical protein
— OG7
C4B63_34g120 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_470g10 ⚠
RNA editing associated helicase 2
— OG6
C4B63_470g11 ⚠
conserved hypothetical protein
— OG6
C4B63_7g282 ⚠
ATP-dependent RNA helicase
— OG6
C4B63_470g9 ⚠
conserved hypothetical protein
— OG6
C4B63_19g248 ⚠
Mitochondrial SSU ribosomal protein
— Both
C4B63_19g249 ⚠
Mitochondrial SSU ribosomal protein
— Both
C4B63_79g90 ⚠
conserved hypothetical protein
— Both
C4B63_181g2 ⚠
conserved hypothetical protein
— Both
C4B63_181g1 ⚠
conserved hypothetical protein
— Both
C4B63_63g48
RNA editing complex protein
— Both
C4B63_93g67 ⚠
RNA editing ligase
— Both
C4B63_11g93
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_42g200
bystin
— Both
C4B63_44g192
mitochondrial RNA binding protein
— Both
C4B63_109g39 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
C4B63_20g158
mitochondrial RNA binding protein
— Both
C4B63_9g433 ⚠
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_2g442
Mitochondrial SSU ribosomal protein
— Both
C4B63_44g193
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_10g495
Serine/threonine-protein kinase RIO1
— Both
C4B63_113g39
MRB1-associated protein
— OG6
C4B63_30g130
mRNA processing protein
— Both
C4B63_9g321
guide RNA associated protein, GAP1
— Both
C4B63_9g442
kinteoplast poly(A) polymerase complex 1 subu
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.