CFAC1_260050100

formate--tetrahydrofolate ligase
Crithidia fasciculata strain Cf-Cl OG6: OG6_100216 OG7: OG7_0002740 203 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 203 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
CFAC1_060012300 ⚠
quinone oxidoreductase, putative
— OG6
CFAC1_070010500 ⚠
hypothetical protein, conserved
— Both
CFAC1_290017700 ⚠
Glucosidase II beta subunit-like/Glucosidase
— Both
CFAC1_170016800 ⚠
ABC transport system ATP-binding protein, put
— Both
CFAC1_190029900 ⚠
iron superoxide dismutase, putative
— OG6
CFAC1_140018800 ⚠
UDP-glucose pyrophosphorylase
— OG6
CFAC1_240023700 ⚠
dephospho-CoA kinase, putative
— OG6
CFAC1_240029400 ⚠
hypothetical protein, conserved
— Both
CFAC1_270064100 ⚠
KH domain/Domain of unknown function (DUF1771
— OG6
CFAC1_220017400 ⚠
protein kinase, putative
— Both
CFAC1_290030000 ⚠
CS domain containing protein, putative
— OG6
CFAC1_240025800 ⚠
pyruvate kinase
— OG6
CFAC1_260006200 ⚠
hypothetical protein, conserved
— Both
CFAC1_250016500 ⚠
eukaryotic translation initiation factor 6 (e
— OG6
CFAC1_290048200 ⚠
pyroglutamyl-peptidase I (C15 family)
— OG6
CFAC1_040010900 ⚠
dihydroxyacetone kinase 1-like protein
— Both
CFAC1_280076200 ⚠
hypothetical protein, conserved
— OG6
CFAC1_260014700 ⚠
monothiol glutaredoxin, putative
— OG6
CFAC1_260025400 ⚠
Phosphatidylinositol-specific phospholipase C
— OG6
CFAC1_180019300 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
CFAC1_230011400 ⚠
hypothetical protein, conserved
— Both
CFAC1_260050200 ⚠
RNA-binding protein, putative
— OG6
CFAC1_300050800 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— OG6
CFAC1_280016400 ⚠
WD domain, G-beta repeat, putative
— OG6
CFAC1_240036500 ⚠
protein kinase, putative
— Both
CFAC1_270008900 ⚠
Sucrase/ferredoxin-like, putative
— OG6
CFAC1_270033300 ⚠
diphthine synthase-like protein
— OG6
CFAC1_280070100 ⚠
Sucrase/ferredoxin-like, putative
— OG6
CFAC1_190037100 ⚠
hypothetical protein, conserved
— OG6
CFAC1_260056300 ⚠
valyl-tRNA synthetase, putative
— Both
CFAC1_250028200 ⚠
exoribonuclease 2, putative
— OG6
CFAC1_200028800 ⚠
UDP-glucose:Glycoprotein Glucosyltransferase,
— Both
CFAC1_040007800 ⚠
mitogen-activated protein kinase, putative
— OG6
CFAC1_250012900 ⚠
Elongation factor G1, mitochondrial, putative
— OG6
CFAC1_240025700 ⚠
pyruvate kinase
— OG6
CFAC1_230012700 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
CFAC1_070006300 ⚠
inorganic pyrophosphatase, putative
— Both
CFAC1_190032800 ⚠
Cytidylyltransferase, putative
— OG6
CFAC1_190018600 ⚠
Alpha/beta hydrolase family, putative
— OG6
CFAC1_300065900 ⚠
alpha glucosidase II subunit, putative
— Both
CFAC1_280070800 ⚠
small G-protein, putative
— OG6
CFAC1_190039700 ⚠
superoxide dismutase, putative
— OG6
CFAC1_220008900 ⚠
cleavage and polyadenylation specificity fact
— Both
CFAC1_230012800 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
CFAC1_150007000 ⚠
GDP-mannose pyrophosphorylase
— Both
CFAC1_260013000 ⚠
phosphoglucomutase, putative
— OG6
CFAC1_220025800 ⚠
5'-3' exonuclease, putative
— OG6
CFAC1_250011200 ⚠
amino acid permease-like protein
— OG6
CFAC1_220039800 ⚠
leucyl-tRNA synthetase, putative
— Both
CFAC1_140014700 ⚠
serine/threonine kinase-like protein, putativ
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.