LINF_030014900

eukaryotic initiation factor 2a - putative
Leishmania infantum JPCM5 OG6: OG6_101220 OG7: OG7_0006220 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_310028700 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_280010100 ⚠
hypothetical protein - conserved
— Both
LINF_300017700 ⚠
small nuclear ribonucleoprotein polypeptide e
— Both
LINF_260024900
hypothetical protein - conserved
— Both
LINF_090018100 ⚠
translation initiation factor EIF-2B gamma su
— Both
LINF_130019800
hypothetical protein - conserved
— Both
LINF_310023900 ⚠
MYND finger containing protein - putative
— OG7
LINF_350041000 ⚠
CRAL/TRIO - N-terminal domain/CRAL/TRIO domai
— OG7
LINF_300021700 ⚠
CRAL/TRIO - N-terminal domain/CRAL/TRIO domai
— OG7
LINF_320018400 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_360042900 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_320018300 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_310028500 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_230010200
SNF1-related protein kinase regulatory subuni
— Both
LINF_310028600 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_250016200 ⚠
dehydrogenase-like protein
— OG7
LINF_300014500 ⚠
adenosine kinase-like protein
— OG7
LINF_150005800 ⚠
ATP-dependent protease ATPase subunit HslU1 -
— OG7
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_320016400 ⚠
small nuclear ribonucleoprotein - putative
— OG7
LINF_350050400 ⚠
sm-f snRNP core complex protein - putative
— OG7
LINF_090018200 ⚠
translation initiation factor EIF-2B gamma su
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_260005000 ⚠
Lsm7p protein - putative
— OG7
LINF_040005800 ⚠
hypothetical protein - conserved
— OG7
LINF_300014400 ⚠
adenosine kinase - putative
— Both
LINF_260024400
deoxyhypusine hydroxylase - putative
— Both
LINF_200011900
serine/threonine protein phosphatase 2A regul
— Both
LINF_110008400 ⚠
14-3-3 protein 2 - putative
— Both
LINF_360044000
Domain of unknown function (DUF3846)/TPR repe
— OG6
LINF_210012000
phosphoglucomutase - putative
— Both
LINF_360011400 ⚠
sec14, cytosolic factor
— Both
LINF_090011900
cyclin 1
— Both
LINF_360040400 ⚠
14-3-3 protein 1 - putative
— Both
LINF_180017700 ⚠
prolyl-tRNA synthetase - putative
— Both
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— Both
LINF_300006800 ⚠
2-hydroxy-3-oxopropionate reductase - putativ
— Both
LINF_050016300 ⚠
Nodulation protein S (NodS)/Methyltransferase
— Both
LINF_340043400 ⚠
adenosine kinase-like protein
— Both
LINF_330012400
hypothetical protein - conserved
— Both
LINF_300038700
UV excision repair RAD23-like protein
— Both
LINF_330036600
MRB1-associated protein
— Both
LINF_090007900 ⚠
ATP-dependent protease ATPase subunit HslU
— Both
LINF_220011900
guide RNA associated protein - GAP2 - putativ
— Both
LINF_080010700
eukaryotic translation initiation factor 2 be
— Both
LINF_080006200
hypothetical protein - conserved
— Both
LINF_350045100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LINF_350045600 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LINF_180016200 ⚠
protein kinase A catalytic subunit
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.