LINF_290012900

U-box domain protein - putative
Leishmania infantum JPCM5 OG6: OG6_138193 OG7: OG7_0002548 135 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 135 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_280026600 ⚠
protein kinase - putative
— OG7
LINF_280016800 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_180007900 ⚠
Dephospho-CoA kinase - putative
— Both
LINF_360010600 ⚠
protein phosphatase 2C-like protein
— OG6
LINF_320022600 ⚠
protein phosphatase 2C - putative
— OG6
LINF_280017100 ⚠
electron-transfer-flavoprotein - alpha polype
— Both
LINF_230025500 ⚠
alanine racemase - putative
— Both
LINF_270030600 ⚠
protein phosphatase-like protein
— OG6
LINF_220008200 ⚠
SEP domain containing protein - putative
— Both
LINF_320014700 ⚠
Alpha/beta hydrolase family - putative
— Both
LINF_340045400 ⚠
phosphomannomutase-like protein
— Both
LINF_270032100 ⚠
TPR-repeat protein - putative
— OG6
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_200011400 ⚠
hypothetical protein - conserved
— Both
LINF_210005600 ⚠
BAR domain containing protein - putative
— Both
LINF_360011200 ⚠
Elongation factor G1 - mitochondrial - putati
— Both
LINF_320005800 ⚠
N-myristoyl transferase - putative
— Both
LINF_280027300 ⚠
Telomere recombination/Putative GTP-binding c
— Both
LINF_160011100 ⚠
dihydroorotase - putative
— Both
LINF_310006400 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_010007100
cyclophilin 12 - putative
— OG6
LINF_330017000 ⚠
nicotinate phosphoribosyltransferase - putati
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_080009900 ⚠
hypothetical protein - conserved
— Both
LINF_180015200 ⚠
UDP-glucose pyrophosphorylase
— Both
LINF_120005100 ⚠
PITH domain-containing protein
— Both
LINF_210006900 ⚠
serine/threonine-protein kinase-like protein
— OG7
LINF_360014700 ⚠
SNF1-related protein kinases - putative
— OG7
LINF_330025600 ⚠
protein kinase - putative
— OG7
LINF_220014000 ⚠
serine/threonine protein kinase sos2 - putati
— OG7
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_320031200 ⚠
Cid1 family poly A polymerase - putative
— OG7
LINF_280019600 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LINF_280019200 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LINF_280019300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LINF_170018800 ⚠
5'-3' exoribonuclease B - putative
— OG7
LINF_150007700 ⚠
sterol carrier protein - putative
— OG7
LINF_360010900 ⚠
ubiquitin-like protein - putative
— OG7
LINF_130012200 ⚠
ubiquitin-like protein
— OG7
LINF_210027200 ⚠
RNA polymerase II - putative
— OG7
LINF_010007000 ⚠
UBA/TS-N domain/CUE domain/Domain of unknown
— OG7
LINF_240006800 ⚠
transcription elongation factor - putative
— OG7
LINF_210005500 ⚠
hypothetical protein - conserved
— OG7
LINF_220008400 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LINF_300009600 ⚠
eukaryotic translation initiation factor 4E -
— OG7
LINF_280032200 ⚠
eukaryotic translation initiation factor 4E -
— OG7
LINF_280019400 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.