LINF_300011700

Phosphoinositide-specific phospholipase C - efhand-like/Phosphatidylinositol-specific phospholipase C - X domain/PDZ domain (Also known as DHR or GLGF)/PDZ domain containing protein - putative
Leishmania infantum JPCM5 OG6: OG6_146793 OG7: OG7_0037550 185 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 185 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_360024300 ⚠
5'-3' exoribonuclease D - putative
— Both
LINF_050006800
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LINF_260007500
hypothetical protein - conserved
— Both
LINF_030014800 ⚠
MORN repeat - putative
— Both
LINF_220022600
CCR4 associated factor - putative
— Both
LINF_040012000
Axonemal dynein light chain - putative
— Both
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— Both
LINF_190011800 ⚠
kinesin - putative
— OG6
LINF_190011700 ⚠
kinesin - putative
— OG6
LINF_300005500
MATH domain containing protein - putative
— Both
LINF_280019500 ⚠
haloacid dehalogenase-like hydrolase - putati
— Both
LINF_240008500 ⚠
aspartate aminotransferase - putative
— Both
LINF_350012900 ⚠
aspartate aminotransferase - putative
— Both
LINF_150015800
hypothetical protein - conserved
— Both
LINF_280016800
WD domain - G-beta repeat - putative
— Both
LINF_280017100
electron-transfer-flavoprotein - alpha polype
— Both
LINF_230025500
alanine racemase - putative
— Both
LINF_220008200
SEP domain containing protein - putative
— Both
LINF_120011300 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— Both
LINF_280027300
Telomere recombination/Putative GTP-binding c
— Both
LINF_310006400
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_060017400
hypothetical protein - conserved
— Both
LINF_360074000 ⚠
ubiquitin-protein ligase - putative
— Both
LINF_360015800
intraflagellar transport protein 122 - putati
— Both
LINF_350045100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LINF_350045600 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LINF_310040100
hypothetical protein - conserved
— Both
LINF_180016200 ⚠
protein kinase A catalytic subunit
— OG6
LINF_300027500
endosomal trafficking protein RME-8 - putativ
— Both
LINF_300012300
CDC16 - putative
— Both
LINF_320008200
intraflagellar transport protein 140 - putati
— Both
LINF_320007600
hypothetical protein - conserved
— Both
LINF_320019100
cleavage and polyadenylation specificity fact
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_090019500
AAA family ATPase - putative
— Both
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_050016100 ⚠
Phosphatidylinositol 4-phosphate 5-kinase - p
— OG7
LINF_340029900 ⚠
Sec7 domain containing protein - putative
— OG7
LINF_340031100 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LINF_080013100
hypothetical protein - conserved
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_320043900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LINF_280026100 ⚠
Elongation factor G 2 - mitochondrial - putat
— OG7
LINF_290027900 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.