LPAL13_320043200

exosome-associated protein 2, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100420 OG7: OG7_0002825 73 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 73 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_140005000 ⚠ exosome complex exonuclease, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010369 OG6 Tb927.6.670 ↔ Tb927.7.4670 OG6 Tb927.11.16600 ↔ Tb927.7.4670 OG6 LdBPK_140010.1 ↔ LdBPK_221430.1 +4 more	Both
LPAL13_040007100 ⚠ exosome complex exonuclease RRP40, putative	—	OG6 LdBPK_040130.1 ↔ LdBPK_221430.1 OG6 Tb927.6.670 ↔ Tb927.9.7070 OG6 Tb927.11.16600 ↔ Tb927.9.7070 OG7 Tb927.6.670 ↔ Tb927.9.7070 +2 more	Both
LPAL13_350058600 ⚠ exosome-associated protein 4, putative	—	OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 LdBPK_020290.1 ↔ LdBPK_221430.1	OG7
LPAL13_350038400 ⚠ exosome complex exonuclease RRP41, putative	—	OG6 Tb927.10.7450 ↔ Tb927.6.670 OG6 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 +2 more	Both
LPAL13_000009900 ⚠ exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG6 LdBPK_044330.1 ↔ LdBPK_221430.1 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG7 LdBPK_044330.1 ↔ LdBPK_221430.1	Both
LPAL13_280036000 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LPAL13_190005500 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LPAL13_280035900 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LPAL13_280036500 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710	OG6
LPAL13_280018900 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LPAL13_260017100 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LPAL13_230025100 ⚠ Csl4p homologue, putative	—	OG6 Tb927.11.16600 ↔ Tb927.5.1200 OG6 Tb927.5.1200 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.5.1200 OG7 Tb927.5.1200 ↔ Tb927.6.670	Both
LPAL13_230021400 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
LPAL13_220018400 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 Tb927.11.16600 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.6.670	Both
LPAL13_280006300 ⚠ proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
LPAL13_200013200 ⚠ elongation factor 1-beta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LPAL13_200012700 ⚠ elongation factor 1-beta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LPAL13_350020400 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LPAL13_340027200 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001893	OG6
LPAL13_000035700 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009798 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009798	Both
LPAL13_190015100 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010718	OG7
LPAL13_340044800 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LPAL13_210025100 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LPAL13_270019900 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LPAL13_350038200 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004479	OG7
LPAL13_000015500 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	OG7
LPAL13_270007400 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LPAL13_350080800 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LPAL13_140008100 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LPAL13_200048300 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LPAL13_030010800 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008440	OG7
LPAL13_350022400 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LPAL13_130020000 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LPAL13_260009600 ⚠ Conserved hypothetical ATP binding protein, p	—	OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	OG7
LPAL13_310006600 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LPAL13_260013400 ⚠ heat shock 70 protein-like protein	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LPAL13_010010200 ⚠ HSP70-like protein	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LPAL13_340053700 ⚠ Hsp70 protein, putative	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LPAL13_200007400 ⚠ eukaryotic translation initiation factor 5, p	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LPAL13_090018700 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006797 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006797	Both
LPAL13_330027400 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
LPAL13_300018300 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003184 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003184	Both
LPAL13_200017600 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003934 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003934	Both
LPAL13_120005200 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LPAL13_350063900 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
LPAL13_210024100 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LPAL13_340054800 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LPAL13_140016700 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both
LPAL13_250019900 ⚠ Conserved hypothetical ATP binding protein, p	—	OG6 Tb927.3.1150 ↔ Tb927.6.670 OG6 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	Both
LPAL13_190005300 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_001893	Both

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