LPAL13_200007400

eukaryotic translation initiation factor 5, putative

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101859 OG7: OG7_0007078 58 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 58 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_140008100 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LPAL13_340035800 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005835 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	Both
LPAL13_270015800 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LPAL13_340044600 ⚠ proteasome beta 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
LPAL13_340027200 ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
LPAL13_300034700 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
LPAL13_310036200 acetyl-CoA carboxylase, putative	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
LPAL13_280006300 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
LPAL13_190005500 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	Both
LPAL13_130020000 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LPAL13_350080800 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LPAL13_270019900 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LPAL13_340044800 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LPAL13_350038200 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	OG7
LPAL13_350022400 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LPAL13_070014500 splicing factor ptsr1-like protein	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009720 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009720	Both
LPAL13_270007400 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LPAL13_210025100 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	OG7
LPAL13_030010800 hypothetical protein, conserved	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008440	OG7
LPAL13_070008800 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_070008900 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_190011000 ⚠ RNA binding protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
LPAL13_000015500 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
LPAL13_320009100 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_350028300 ⚠ DEAD box RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_350023000 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
LPAL13_100006300 ⚠ DEAD/DEAH box helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_080005700 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_280028300 ⚠ mitochondrial DEAD box protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LPAL13_340054800 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	Both
LPAL13_200029500 RNA recognition motif. (a.k.a. RRM, RBD, or R	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6
LPAL13_350058800 hypothetical protein, conserved	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
LPAL13_270030200 ⚠ Thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LPAL13_320037700 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LPAL13_300011200 spliceosome-associated protein, putative	—	OG6 TCSYLVIO_003119 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003119 ↔ TCSYLVIO_004556	Both
LPAL13_030011000 ⚠ DEAD/DEAH box helicase/Helicase conserved C-t	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
LPAL13_000009900 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
LPAL13_190005300 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
LPAL13_220018400 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LPAL13_320043200 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LPAL13_320016000 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LPAL13_230021400 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LPAL13_030006100 acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
LPAL13_350043400 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LPAL13_290019200 hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_004556	Both
LPAL13_210024100 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369	Both
LPAL13_350063900 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LPAL13_120005200 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
LPAL13_170018800 translation initiation factor, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_008900 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008900	Both
LPAL13_000045600 ⚠ 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both

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