LTRL590_190020000

inosine-5'-monophosphate dehydrogenase
Leishmania tropica L590 OG6: OG6_100534 OG7: OG7_0002926 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_110013100 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LTRL590_310008300 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LTRL590_330038800 ⚠
hypothetical protein
— OG7
LTRL590_210016500 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_290011700 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LTRL590_300010300 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LTRL590_270013900 ⚠
hypothetical protein, conserved
— OG6
LTRL590_180015900 ⚠
5-oxoprolinase, putative
— Both
LTRL590_320013200 ⚠
RNA binding protein, putative
— OG6
LTRL590_030014600 ⚠
peter pan protein, putative
— OG6
LTRL590_080009500 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_110016100 ⚠
Leucine Rich repeat, putative
— Both
LTRL590_260030600 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
LTRL590_260005000 ⚠
brix domain containing-like protein
— OG6
LTRL590_160021000 ⚠
EMG1/NEP1 methyltransferase, putative
— OG6
LTRL590_310039700 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LTRL590_250018500 ⚠
ATPase beta subunit, putative
— Both
LTRL590_360031500 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LTRL590_300011900 ⚠
ribosome biogenesis regulatory protein (RRS1)
— OG6
LTRL590_160011200 ⚠
carbamoyl-phosphate synthase, putative
— Both
LTRL590_160011100 ⚠
carbamoyl-phosphate synthase, putative
— Both
LTRL590_250018400 ⚠
ATPase beta subunit, putative
— Both
LTRL590_350018000 ⚠
hypothetical protein, conserved
— OG6
LTRL590_350054300 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LTRL590_330029900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330029700 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360039400 ⚠
ATP-dependent RNA helicase, putative
— OG7
LTRL590_350041200 ⚠
zinc finger protein, putative
— OG7
LTRL590_190013800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_350049500 ⚠
predicted zinc finger protein
— OG7
LTRL590_260005500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LTRL590_140019300 ⚠
ras-like small GTPases, putative
— OG7
LTRL590_260017400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LTRL590_350005500 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
LTRL590_310039600 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LTRL590_310039500 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LTRL590_060013500
hypothetical protein, conserved
— OG7
LTRL590_090018500 ⚠
hypothetical protein, conserved
— OG7
LTRL590_090018400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_330034200 ⚠
aminopeptidase, putative
— OG7
LTRL590_310008100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_000022400 ⚠
MORN repeat, putative
— OG7
LTRL590_330038900 ⚠
hypothetical protein, conserved
— OG7
LTRL590_340046400 ⚠
geranylgeranyltransferase, putative
— OG7
LTRL590_210015900 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— Both
LTRL590_000019300 ⚠
Leucine-rich repeat - CC (cysteine-containing
— Both
LTRL590_280026200 ⚠
p21-C-terminal region-binding protein, putati
— Both
LTRL590_260013100 ⚠
hypothetical protein, conserved
— Both
LTRL590_350033300 ⚠
Short calmodulin-binding motif containing con
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.